Tuberculosis and nature's pharmacy of putative anti-tuberculosis agents

KC Chinsembu - Acta Tropica, 2016 - Elsevier
Due to the growing problem of drug resistant Mycobacterium tuberculosis strains, coupled
with the twinning of tuberculosis (TB) to human immunodeficiency virus/acquired …

Efficacy and mechanisms of flavonoids against the emerging opportunistic nontuberculous Mycobacteria

S Mickymaray, FA Alfaiz, A Paramasivam - Antibiotics, 2020 - mdpi.com
Nontuberculous mycobacteria (NTM) are the causative agent of severe chronic pulmonary
diseases and is accountable for post-traumatic wound infections, lymphadenitis …

Quercetin 3-O-glucoside recovered from the wild Egyptian Sahara plant, Euphorbia paralias L., inhibits glutamine synthetase and has antimycobacterial activity

NA Safwat, MT Kashef, RK Aziz, KF Amer… - Tuberculosis, 2018 - Elsevier
Tuberculosis remains a major health problem accentuated by the rise of resistance to all
available drugs. Therefore, this study was launched to discover a novel antituberculosis …

Phenolic compounds as promising drug candidates in tuberculosis therapy

MH Mazlun, SF Sabran, M Mohamed, MF Abu Bakar… - Molecules, 2019 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB) remains one of the
deadliest, infectious diseases worldwide. The detrimental effects caused by the existing anti …

Enantioselective Dearomative [4+2] Cycloaddition Reaction of 1‐Naphthols with In‐Situ Generated ortho‐Quinone Methides

S Ranjan Sahoo, K Gupta… - Chemistry–A European …, 2023 - Wiley Online Library
We disclose a catalytic, enantioselective dearomative reaction of non‐functionalized 1‐
naphthols, which poses a synthetic challenge to organic chemists because of the relative …

Synthesis of Naphthopyrans via Formal (3+3)-Annulation of Propargylic (Aza)-para-Quinone Methides with Naphthols

XZ Zhang, BQ Li, ZW Qiu, AJ Ma, JB Peng… - The Journal of …, 2020 - ACS Publications
Herein, we report an efficient Brønsted acid-catalyzed formal (3+ 3)-annulation of (aza)-para-
quinone methides generated in situ from propargylic alcohols with naphthol derivatives …

An overview of phytotherapeutic approaches for the treatment of tuberculosis

D Sharma, J Parkash Yadav - Mini reviews in medicinal …, 2017 - ingentaconnect.com
Tuberculosis (TB) is highly infectious disease causing morbidity and death. Its causative
organism is a contagious bacterium, Mycobacterium tuberculosis. The incidence of …

Synthesis, antitubercular activity and molecular docking study of substituted [1,3]dioxino[4,5-d]pyrimidine derivatives via facile CAN catalyzed Biginelli reaction

T Venkatesh, YD Bodke, B Manjunatha… - … Nucleotides & Nucleic …, 2021 - Taylor & Francis
We have developed a simple and convenient method for the synthesis of substituted-
aryllidine-2, 2-dimethyl-7-thioxo/oxo-4H-[1, 3] dioxino [4, 5-d] pyrimidine derivatives (4a-g) …

An enantioselective assembly of naphthopyran via NHC-catalyzed [3+ 3] annulation of bromoenal with β-tetralone

S Li, Y Yao, Z Tang, B Sun, C Yu, T Li… - Organic & Biomolecular …, 2019 - pubs.rsc.org
An asymmetric assembly of naphthopyran was realized via the N-heterocyclic carbene
(NHC)-catalyzed formal [3+ 3] annulation of bromoenal and β-tetralone. The key advantages …

[HTML][HTML] Avaliação da atividade antimicobacteriana da lignana diidrocubebina extraída da Piper cubeba e de seus derivados semissintéticos

RS Laurentiz, A Borges, AC Laurentiz… - Revista brasileira de …, 2015 - SciELO Brasil
RESUMO A atividade antimicobacteriana de diidrocubebina (1), uma lignana
dibenzilbutanodioica obtida a partir de extrato etanólico de sementes da Piper cubeba, e …