In contrast to all other organs, liver‐to‐body‐weight ratio needs to be maintained always at 100% of what is required for body homeostasis. Adjustment of liver size to 100% of what is …
GK Michalopoulos - The liver: biology and pathobiology, 2020 - Wiley Online Library
Signals related to liver regeneration (LR) have been identified by triggering proliferation in hepatocyte cultures, delay of regeneration associated with signal ablation in genomically …
Liver regeneration is perhaps the most studied example of compensatory growth aimed to replace loss of tissue in an organ. Hepatocytes, the main functional cells of the liver, manage …
N Fausto, AD Laird, EM Webber - The FASEB Journal, 1995 - Wiley Online Library
During liver regeneration quiescent hepatocytes undergo one or two rounds of replication and then return to a nonproliferative state. Growth factors regulate this process by providing …
T de Baere, A Roche, D Elias, P Lasser, C Lagrange… - Hepatology, 1996 - journals.lww.com
To render hepatectomy feasible in patients with an initially deficient volume of the future remnant liver (FRL), we redistributed portal blood flow rich in hepatotrophic substances …
Drs. Busuttil and Klintmalm present Transplantation of the Liver, 3rd Edition, which has been thoroughly revised to offer you the latest protocols, surgical approaches, and techniques …
Liver regeneration is a complex phenomenon aimed at maintaining a constant liver mass in the event of injury resulting in loss of hepatic parenchyma. Partial hepatectomy is followed …
M Hagiya, A Francavilla, L Polimeno… - Proceedings of the …, 1994 - National Acad Sciences
A full-length cDNA clone encoding a purified augmenter of liver regeneration (ALR) factor prepared from the cytosol of weanling rat livers was isolated. The 1.2-kb cDNA included a …
EM Webber, PJ Godowski, N Fausto - Hepatology, 1994 - journals.lww.com
Although growth factor effects have been studied in cultured hepatocytes, little information exists as to whether these factors can trigger hepatocyte replication in vivo. In this study we …