Human gut microbiota in health and disease: Unveiling the relationship

M Afzaal, F Saeed, YA Shah, M Hussain… - Frontiers in …, 2022 - frontiersin.org
The human gut possesses millions of microbes that define a complex microbial community.
The gut microbiota has been characterized as a vital organ forming its multidirectional …

[HTML][HTML] Gut microbiota imbalance and colorectal cancer

J Gagnière, J Raisch, J Veziant, N Barnich… - World journal of …, 2016 - ncbi.nlm.nih.gov
The gut microbiota acts as a real organ. The symbiotic interactions between resident micro-
organisms and the digestive tract highly contribute to maintain the gut homeostasis …

Altered gut metabolites and microbiota interactions are implicated in colorectal carcinogenesis and can be non-invasive diagnostic biomarkers

OO Coker, C Liu, WKK Wu, SH Wong, W Jia, JJY Sung… - Microbiome, 2022 - Springer
Background Gut microbiota contributes to colorectal cancer (CRC) pathogenesis through
microbes and their metabolites. The importance of microbiota-associated metabolites in …

Gut microbiota in colorectal cancer: biological role and therapeutic opportunities

H Pandey, DWT Tang, SH Wong, D Lal - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …

[HTML][HTML] Emerging roles of lactic acid bacteria in protection against colorectal cancer

L Zhong, X Zhang, M Covasa - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third leading cause of cancer deaths worldwide and the
fourth most common cancer diagnosed among men and women in the United States …

Dietary metabolites derived from gut microbiota: critical modulators of epigenetic changes in mammals

MI Bhat, R Kapila - Nutrition reviews, 2017 - academic.oup.com
The mammalian gastrointestinal tract harbors trillions of commensal microorganisms,
collectively known as the microbiota. The microbiota is a critical source of environmental …

The role of curcumin in modulating colonic microbiota during colitis and colon cancer prevention

RMT McFadden, CB Larmonier… - Inflammatory bowel …, 2015 - academic.oup.com
Background Intestinal microbiota influences the progression of colitis-associated colorectal
cancer. With diet being a key determinant of the gut microbial ecology, dietary interventions …

[HTML][HTML] The role of probiotics in cancer treatment: emphasis on their in vivo and in vitro anti-metastatic effects

E Motevaseli, A Dianatpour… - International journal of …, 2017 - ncbi.nlm.nih.gov
Probiotics are defined as live bacteria and yeasts that exert beneficial effects for health.
Among their various effects, anti-cancer properties have been highlighted in recent years …

The gut microbiota and their metabolites: potential implications for the host epigenome

M Mischke, T Plösch - Microbiota of the human body: implications in health …, 2016 - Springer
The gut microbiota represents a metabolically active biomass of up to 2 kg in adult humans.
Microbiota-derived molecules significantly contribute to the host metabolism. Large amounts …

Microbiome-driven carcinogenesis in colorectal cancer: Models and mechanisms

X Wang, Y Yang, MM Huycke - Free radical biology and medicine, 2017 - Elsevier
Colorectal cancer (CRC) is a leading cause of cancer death and archetype for cancer as a
genetic disease. However, the mechanisms for genetic change and their interactions with …