The emerging role of α-synuclein truncation in aggregation and disease

ZA Sorrentino, BI Giasson - Journal of Biological Chemistry, 2020 - ASBMB
α-Synuclein (αsyn) is an abundant brain neuronal protein that can misfold and polymerize to
form toxic fibrils coalescing into pathologic inclusions in neurodegenerative diseases …

Aggregation promoting C-terminal truncation of α-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

W Li, N West, E Colla, O Pletnikova… - Proceedings of the …, 2005 - National Acad Sciences
Abnormal biology of α-synuclein (α-Syn) is directly implicated in the pathogenesis of
Parkinson's disease and other α-synucleinopathies. Herein, we demonstrate that C …

Cell-to-cell and long-distance trafficking of the green fluorescent protein in the phloem and symplastic unloading of the protein into sink tissues

A Imlau, E Truernit, N Sauer - The Plant Cell, 1999 - academic.oup.com
Macromolecular trafficking within the sieve element–companion cell complex, phloem
unloading, and post-phloem transport were studied using the jellyfish green fluorescent …

The expression and posttranslational modification of a neuron‐specific β‐tubulin isotype during chick embryogenesis

MK Lee, JB Tuttle, LI Rebhun… - Cell motility and the …, 1990 - Wiley Online Library
Five β‐tubulin isotypes are expressed differentially during chicken brain development. One
of these isotypes is encoded by the gene cβ4 and has been assigned to an isotypic family …

Interaction between heat shock proteins and antimicrobial peptides

L Otvos, IO, ME Rogers, PJ Consolvo, BA Condie… - Biochemistry, 2000 - ACS Publications
Drosocin, pyrrhocoricin, and apidaecin, representing the short (18− 20 amino acid residues)
proline-rich antibacterial peptide family, originally isolated from insects, were shown to act …

A coiled‐coil related protein specific for synapsed regions of meiotic prophase chromosomes.

RL Meuwissen, HH Offenberg, AJ Dietrich… - The EMBO …, 1992 - embopress.org
Synaptonemal complexes (SCs) are structures that are formed between homologous
chromosomes during meiotic prophase. They are probably involved in chromosome pairing …

Systematic screening of all signal peptides from Bacillus subtilis: a powerful strategy in optimizing heterologous protein secretion in Gram-positive bacteria

U Brockmeier, M Caspers, R Freudl, A Jockwer… - Journal of molecular …, 2006 - Elsevier
Efficient protein secretion is very important in biotechnology as it provides active and stable
enzymes, which are an essential prerequisite for successful biocatalysis. Therefore …

αB subunit of lens-specific protein α-crystallin is present in other ocular and non-ocular tissues

SP Bhat, CN Nagineni - Biochemical and biophysical research …, 1989 - Elsevier
α-Crystallin, a tissue specific structural protein of the ocular lens, is known to be composed
of two subunits, αA and αB. By using a specific antibody in an immunoblotting procedure we …

[图书][B] Methods of biochemical analysis

D Glick - 2009 - books.google.com
Biochemical analysis is a rapidly expanding field and is a key component of modern drug
discovery and research. Methods of Biochemical Analysis provides a periodic and …

The gene encoding a major component of the lateral elements of synaptonemal complexes of the rat is related to X-linked lymphocyte-regulated genes

JHM Lammers, HH Offenberg… - … and cellular biology, 1994 - Am Soc Microbiol
The lateral elements of synaptonemal complexes (SCs) of the rat contain major components
with relative electrophoretic mobilities (M r S) of 30,000 and 33,000. After one-dimensional …