Food allergy is a major health issue, affecting the lives of 8% of US children and their
families. There is an urgent need to identify the environmental and endogenous signals that …

Mastocytosis is a heterogeneous group of neoplasms defined by a numerical increase and
accumulation of clonal mast cells (MCs) in various organ systems. The disease may present …

Abstract Background Chronic inducible urticaria (CIndU) is characterized by mast cell (MC)‐
mediated wheals in response to triggers: cold in cold urticaria (ColdU) and friction in …

Mast cells are unique tissue-resident immune cells of the myeloid lineage that have long
been implicated in the pathogenesis of allergic and autoimmune disorders. More recently …

Mast cells are (in) famous for their role in allergic diseases, but the physiological and
pathophysiological roles of this ingenious cell are still not fully understood. Mast cells are …

The discovery in 1987/1988 and 1990 of the cell surface receptor KIT and its ligand, stem
cell factor (SCF), was a critical achievement in efforts to understand the development and …

Mast cell activation syndromes (MCASs) are defined by systemic severe and recurrent mast
cell activation, usually in form of anaphylaxis, a substantial, event-related increase of the …

Mastocytosis is a myeloid neoplasm defined by expansion and focal accumulation of clonal
mast cells (MCs) in one or more organs. The disease exhibits a complex pathology and may …

Background Mast cells (MC) are powerful inflammatory immune sentinel cells that drive
numerous allergic, inflammatory, and pruritic disorders when activated. MC‐targeted …

The characteristics of the tumour cells, as well as how tumour cells interact with their
surroundings, affect the prognosis of cancer patients. The resident cells in the tumour …