The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Antiviral potential of nanoparticles—can nanoparticles fight against coronaviruses?

S Gurunathan, M Qasim, Y Choi, JT Do, C Park… - Nanomaterials, 2020 - mdpi.com
Infectious diseases account for more than 20% of global mortality and viruses are
responsible for about one-third of these deaths. Highly infectious viral diseases such as …

Heparan sulfate proteoglycans and viral attachment: true receptors or adaptation bias?

V Cagno, ED Tseligka, ST Jones, C Tapparel - Viruses, 2019 - mdpi.com
Heparan sulfate proteoglycans (HSPG) are composed of unbranched, negatively charged
heparan sulfate (HS) polysaccharides attached to a variety of cell surface or extracellular …

Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

Y Cheng, L Zhao, Y Li, T Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …

Nanoparticulate delivery systems for antiviral drugs

D Lembo, R Cavalli - Antiviral Chemistry and Chemotherapy, 2010 - journals.sagepub.com
Nanomedicine opens new therapeutic avenues for attacking viral diseases and for
improving treatment success rates. Nanoparticulate-based systems might change the …

Designer peptide and protein dendrimers: a cross-sectional analysis

R Sapra, RP Verma, GP Maurya, S Dhawan… - Chemical …, 2019 - ACS Publications
Dendrimers have attracted immense interest in science and technology due to their unique
chemical structure that offers a myriad of opportunities for researchers. Dendritic design …

Bioactive peptides: synthesis, properties, and applications in the packaging and preservation of food

PJ Perez Espitia… - … Reviews in Food …, 2012 - Wiley Online Library
Bioactive peptides are protein fragments which have a positive impact on the functions and
conditions of living beings. Peptides have shown several useful properties for human health …

Heparin sensing and binding–taking supramolecular chemistry towards clinical applications

SM Bromfield, E Wilde, DK Smith - Chemical Society Reviews, 2013 - pubs.rsc.org
Heparin is a vital biomolecule in widespread clinical use as an anti-coagulant. Heparin
sensors have potential applications in the bedside detection of heparin levels in human …

Beyond natural antimicrobial peptides: multimeric peptides and other peptidomimetic approaches

A Giuliani, AC Rinaldi - Cellular and Molecular Life Sciences, 2011 - Springer
Naturally occurring antimicrobial peptides (AMPs) present several drawbacks that strongly
limit their development into therapeutically valuable antibiotics. These include susceptibility …

Dendrimers and dendritic materials: From laboratory to medical practice in infectious diseases

MÁ Ortega, A Guzmán Merino, O Fraile-Martínez… - Pharmaceutics, 2020 - mdpi.com
Infectious diseases are one of the main global public health risks, predominantly caused by
viruses, bacteria, fungi, and parasites. The control of infections is founded on three main …