Emerging biomarkers and molecular targets for precision medicine in cervical cancer

P Garg, M Krishna, AR Subbalakshmi… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Cervical cancer remains a significant global health burden, necessitating innovative
approaches for improved diagnostics and personalized treatment strategies. Precision …

Deciphering DNA methylation in HIV infection

T Arumugam, U Ramphal, T Adimulam… - Frontiers in …, 2021 - frontiersin.org
With approximately 38 million people living with HIV/AIDS globally, and a further 1.5 million
new global infections per year, it is imperative that we advance our understanding of all …

Digital loop-mediated isothermal amplification-based absolute methylation quantification revealed hypermethylated DAPK1 in cervical cancer patients

YL Tan, H Chen, ZK Wu, J He, JH Jiang - Analytical chemistry, 2021 - ACS Publications
The aberrant methylation of many genes has been reported to be associated with various
carcinomas. Accurate detection of the methylation level could provide critical insights into …

Increased Gene Expression of C1orf74 Is Associated with Poor Prognosis in Cervical Cancer

P Parida, S Lewis, K Sharan, MV Kamal, NAN Kumar… - Cells, 2023 - mdpi.com
C1orf74, also known as URCL4, has been reported to have higher expression and be
associated with poor prognosis in lung adenocarcinoma patients, and its role in regulation of …

Validation of ASCL1 and LHX8 Methylation Analysis as Primary Cervical Cancer Screening Strategy in South African Women with Human Immunodeficiency Virus

FJ Vink, CJLM Meijer… - Clinical Infectious …, 2023 - academic.oup.com
Background Compared with women who are human immunodeficiency virus (HIV) negative,
women with human immunodeficiency virus (WWH) have a higher human papillomavirus …

MRVI1 and NTRK3 are potential tumor suppressor genes commonly inactivated by DNA methylation in cervical cancer

H Ji, K Li, W Jiang, J Li, JA Zhang, X Zhu - Frontiers in Oncology, 2022 - frontiersin.org
The abnormally methylated tumor suppressor genes (TSGs) associated with cervical cancer
are unclear. DNA methylation data, RNA-seq expression profiles, and overall survival data …

[HTML][HTML] Clinical indications for host-cell DNA methylation markers in cervical screening and management of cervical intraepithelial neoplasia: A review

S Dick, DAM Heideman, J Berkhof… - Tumour virus …, 2024 - Elsevier
DNA methylation of host-cell genes is an epigenetic process that regulates gene expression
and is associated with cervical cancer development. Studies on the natural history of …

[PDF][PDF] Expression and hypermethylation of JAM and EPB41L3 in cervical squamous cell carcinoma: clinical significance and applications

Y Gu, C Chu, B Yuan, J Wang, S Pan - 2024 - hh.um.es
This study aimed to explore the expression and hypermethylation of EPB41L3 and JAM3 in
cervical squamous cell carcinoma (CSCC) and to investigate their clinical significance …

Statistical analysis of DNA methylation patterns of tumor suppressor genes for breast cancer

S Sun, A Pritchard, E McFall, C Tian - 2023 - researchsquare.com
Background Breast cancer is associated with DNA methylation, an epigenetic event in which
a methyl group is covalently bonded to a cytosine-guanine (CG) pair. Although previous …

[PDF][PDF] THE EFFECT OF GENES RELATED TO TUMOR PROGRESSION AND METASTASIS ON CERVICAL CANCER PROGNOSIS

E Balčiūnienė - Sciences - lsmu.lt
Cervical cancer is a widely spread health problem and one of the most common oncological
diseases. According to the World Health Organization, it is women's fourth most commonly …