The Interplay between Ferroptosis and Neuroinflammation in Central Neurological Disorders

Y Xu, B Jia, J Li, Q Li, C Luo - Antioxidants, 2024 - mdpi.com
Central neurological disorders are significant contributors to morbidity, mortality, and long-
term disability globally in modern society. These encompass neurodegenerative diseases …

The role of ferroptosis in neurodegenerative diseases

Y Fei, Y Ding - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Ferroptosis represents an iron− and lipid peroxidation (LPO)-mediated form of regulated cell
death (RCD). Recent evidence strongly suggests the involvement of ferroptosis in various …

NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease

H Wang, W Mao, Y Zhang, W Feng, B Bai, B Ji… - Free Radical Biology …, 2024 - Elsevier
The progressive loss of dopaminergic neurons in the midbrain is the hallmark of Parkinson's
disease (PD). A newly emerging form of lytic cell death, ferroptosis, has been implicated in …

[HTML][HTML] Inhibition of acid-sensing receptor GPR4 attenuates neuronal ferroptosis via RhoA/YAP signaling in a rat model of subarachnoid hemorrhage

Q He, Y Zhou, L Wu, L Huang, Y Yuan, JJ Flores… - Free Radical Biology …, 2024 - Elsevier
Abstract Background and Purpose Subarachnoid hemorrhage (SAH) is a devastating stroke,
in which acidosis is one of detrimental complications. The extracellular pH reduction can …

Menaquinone-4 alleviates hypoxic-ischemic brain damage in neonatal rats by reducing mitochondrial dysfunction via Sirt1-PGC-1α-TFAM signaling pathway

X Feng, Y Zheng, N Mao, M Shen, L Chu… - International …, 2024 - Elsevier
Background Hypoxic-ischemic encephalopathy (HIE) is a major contributor to neonatal
mortality and neurodevelopmental disorders, but currently there is no effective therapy drug …

Menaquinone-4 Alleviates Sepsis-Associated Acute Lung Injury via Activating SIRT3-p53/SLC7A11 Pathway

N Gao, XY Liu, J Chen, TP Hu, Y Wang… - Journal of …, 2024 - Taylor & Francis
Background Sepsis-associated acute lung injury (SI-ALI) is triggered by various direct or
indirect noncardiogenic factors affecting the alveolar epithelium and capillary endothelial …

Ferroptosis in early brain injury after subarachnoid hemorrhage: review of literature

J Kang, S Tian, L Zhang, G Yang - Chinese Neurosurgical Journal, 2024 - Springer
Spontaneous subarachnoid hemorrhage (SAH), mainly caused by ruptured intracranial
aneurysms, is a serious acute cerebrovascular disease. Early brain injury (EBI) is all brain …