Inhibiting bacterial drug efflux pumps via phyto-therapeutics to combat threatening antimicrobial resistance
Antibiotics, once considered the lifeline for treating bacterial infections, are under threat due
to the emergence of threatening antimicrobial resistance (AMR). These drug-resistant …
to the emergence of threatening antimicrobial resistance (AMR). These drug-resistant …
Effectiveness of efflux pump inhibitors as biofilm disruptors and resistance breakers in gram-negative (ESKAPEE) bacteria
Antibiotic resistance represents a significant threat to the modern healthcare provision. The
ESKAPEE pathogens (Enterococcus faecium., Staphylococcus aureus, Klebsiella …
ESKAPEE pathogens (Enterococcus faecium., Staphylococcus aureus, Klebsiella …
Structural and functional diversity of resistance–nodulation–cell division transporters
Multidrug resistant (MDR) bacteria are a global threat with many common infections
becoming increasingly difficult to eliminate. While significant effort has gone into the …
becoming increasingly difficult to eliminate. While significant effort has gone into the …
Natural Alkaloid Berberine Activity against Pseudomonas aeruginosa MexXY-Mediated Aminoglycoside Resistance: In Silico and in Vitro Studies
E Laudadio, N Cedraro, G Mangiaterra… - Journal of natural …, 2019 - ACS Publications
The multidrug efflux system MexXY-OprM, inside the resistance-nodulation-division family, is
a major determinant of aminoglycoside resistance in Pseudomonas aeruginosa. In the fight …
a major determinant of aminoglycoside resistance in Pseudomonas aeruginosa. In the fight …
Efflux-mediated multidrug resistance in critical gram-negative bacteria and natural efflux pump inhibitors
P Nanjan, V Bose - Current Drug Research Reviews Formerly …, 2024 - benthamdirect.com
Multidrug Resistance mechanisms in microorganisms confer the slackness of the existing
drugs, leading to added difficulty in treating infections. As a consequence, efficient novel …
drugs, leading to added difficulty in treating infections. As a consequence, efficient novel …
Early impairment of epigenetic pattern in neurodegeneration: Additional mechanisms behind pyrethroid toxicity
Permethrin is a synthetic pyrethroid extensively used as anti-woodworm agent and for
indoor and outdoor pest control. The main route of human exposure is through fruit …
indoor and outdoor pest control. The main route of human exposure is through fruit …
Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump
Transporters of the resistance-nodulation-cell division (RND) superfamily of proteins are the
dominant multidrug efflux power of Gram-negative bacteria. The major RND efflux pump of …
dominant multidrug efflux power of Gram-negative bacteria. The major RND efflux pump of …
Synthesis, characterization and antioxidant properties of a new lipophilic derivative of edaravone
C Minnelli, E Laudadio, R Galeazzi, D Rusciano… - Antioxidants, 2019 - mdpi.com
As part of a program aimed to obtain antioxidants able to interact with cell membrane,
edaravone (EdV, 3-methyl-1-phenyl-2-pyrazolin-5-one), a well-known free radical …
edaravone (EdV, 3-methyl-1-phenyl-2-pyrazolin-5-one), a well-known free radical …
Structure based virtual screening for identification of potential quorum sensing inhibitors against LasR master regulator in Pseudomonas aeruginosa
Inter and intracellular communication in bacteria, which is known as quorum sensing (QS), is
mediated by small diffusible signaling molecules known as autoinducers. QS regulates …
mediated by small diffusible signaling molecules known as autoinducers. QS regulates …
[HTML][HTML] Effect of black pepper essential oil on quorum sensing and efflux pump systems in the fish-borne spoiler Pseudomonas psychrophila KM02 identified by RNA …
Given the increasing consumption of aquatic foods and green consumerism, efficient
methods for extending the shelf-life and maintaining the safety of seafood are urgently …
methods for extending the shelf-life and maintaining the safety of seafood are urgently …