Although the diagnosis of mycobacteriosis and susceptibility testing are still primarily based
on conventional methods (staining, culture, biochemical analysis, proportional method), a …

New genotypic and phenotypic methods for rapid diagnosis and detection of drug resistance
have been developed and tested both in M. tuberculosis strains as well as in clinical …

Background Hundreds of studies have evaluated the diagnostic accuracy of nucleic-acid
amplification tests (NAATs) for tuberculosis (TB). Commercial tests have been shown to give …

OBJECTIVE: A new loop-mediated isothermal amplification (LAMP) test kit, including a
simple DNA extraction device for the detection of Mycobacterium tuberculosis complex, was …

Traditionally, solid culture media for mycobacteria are kept for up to 8 weeks before a
negative result is reported to the physician. Even though it is well documented that liquid …

Nucleic acid-based amplification tests allow the rapid detection of Mycobacterium
tuberculosis. Recently, a real-time PCR assay for M. tuberculosis complex, the Cobas …

ABSTRACT We evaluated GenoType Mycobacteria Direct (GTMD), a novel commercial
assay based on nucleic acid sequence-based amplification technology, for the detection of …

Objectives Loop-mediated isothermal amplification (LAMP) is a newly developed molecular
method that can be performed isothermally. We developed and evaluated a LAMP assay …

Abstract Background With Fluorotype MTB (FT MTB, HAIN Lifesciences, Germany) a new
semi-automated assay for detection of M. tuberculosis complex (MTBC) in clinical …

Molecular assays have not yet been able to replace time-consuming culture-based methods
in clinical mycobacteriology. Using 6875 clinical samples and a study period of 35months …