Tissue remodeling in pulmonary disease irreversibly alters lung functionality and impacts
quality of life. Mechanical ventilation is amongst the few pulmonary interventions to aid …

Anterior cruciate ligament (ACL) injury rates are rising, and there is little consensus about
what puts someone at risk for an ACL injury. Finite element models provide an effective …

Background: Replacing damaged anterior cruciate ligaments (ACLs) with tissue-engineered
artificial ligaments is challenging because ligament scaffolds must have a multiregional …

Soft tissue injuries (such as ligament, tendon, and meniscus tears) are the result of
extracellular matrix damage from excessive tissue stretching. Deformation thresholds for soft …

Contemporary material characterization techniques that leverage deformation fields and the
weak form of the equilibrium equations face challenges in the numerical solution procedure …

The mechanical properties of soft tissues are driven by their complex, heterogeneous
composition and structure. Interestingly, studies of soft tissue biomechanics often ignore …

Purpose Certain types of repetitive sub-maximal knee loading cause microfatigue damage
in the human anterior cruciate ligament (ACL) that can accumulate to produce macroscopic …

Pelvic organ prolapse is a debilitating condition that diminishes quality of life, and it has
been linked to pregnancy and aging. Injury of the uterosacral ligaments (USLs), which …

Many cartilage tissues in the body fail to heal after injury. Two of these tissues are growth
plate cartilage and articular cartilage. Tissue engineering is a promising strategy for treating …