Extensive studies showed that monoaminergic neurotransmission that involves serotonin (5-
HT), norepinephrine (NE) and dopamine (DA) exerts major influence on brain circuits …

Prescribing of antidepressant treatment (ADT) for major depressive disorder (MDD) has
increased in quantity and popularity over the last two decades. This is likely due to the …

Background: A meta-analysis of the efficacy and tolerability of selective serotonin reuptake
inhibitors (SSRIs) against tricyclic antidepressants (TCAs) in depressed patients was carried …

The selective serotonin reuptake inhibitors (SSRIs) have emerged as a major therapeutic
advance in psychopharmacology. As a result, the discovery of these agents marks a …

Background: Recent reports describe discontinuation-emergent adverse events upon
cessation of selective serotonin reuptake inhibitors including dizziness, insomnia …

Background Depressive disorders are common in young people and are associated with
significant negative impacts. Newer generation antidepressants, particularly selective …

This book examines the well-being of people with mental illness in the United States over
the past fifty years, addressing issues such as economics, treatment, standards of living …

The monoamine hypothesis of depression has dominated our understanding of both the
pathophysiology of depression and the action of pharmacological treatments for the last …

Background: Despite treatment advances, major depressive disorder (MDD) is still a
significant cause of morbidity and mortality. Current therapies frequently fall short of …

A revision of the British Association for Psychopharmacology guidelines for treating
depressive disorders with antidepressants was undertaken in order to specify the scope and …