A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Ischemic stroke is one of the major causes of morbidity and mortality, affecting millions of
people worldwide. Inevitably, the interruption of cerebral blood supply after ischemia may …

The sirtuin system consists of seven highly conserved regulatory enzymes responsible for
metabolism, antioxidant protection, and cell cycle regulation. The great interest in sirtuins is …

Cerebral ischemia, also known as ischemic stroke, accounts for nearly 85% of all strokes
and is the leading cause of disability worldwide. Due to disrupted blood supply to the brain …

Cell death is a process consequential to cerebral ischemia and cerebral
ischemia/reperfusion (I/R) injury. Recent evidence suggest that necroptosis has been …

Over the past few decades, mechanisms of programmed cell death have attracted the
scientific community because they are involved in diverse human diseases. Initially …

Cell death has a fundamental impact on the evolution of degenerative disorders,
autoimmune processes, inflammatory diseases, tumor formation and immune surveillance …

Neonatal hypoxic-ischemic brain injury (HIBI) is a knotty disease that lacks appropriate
treatment. Inflammation is an important contributor to brain damage, and microglia are …

Melanoma as the most major skin malignancy has attracted much attention, so far. Although
a successful therapeutic strategy requires an accurate understanding of the precise …

Background Stroke serves as a prevalent cerebrovascular disorder with severe cerebral
ischemia/reperfusion (CIR) injury, in which neural stem cells (NSCs) play critical roles in the …