The thioredoxin antioxidant system

J Lu, A Holmgren - Free radical biology and medicine, 2014 - Elsevier
The thioredoxin (Trx) system, which is composed of NADPH, thioredoxin reductase (TrxR),
and thioredoxin, is a key antioxidant system in defense against oxidative stress through its …

Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Survival of Helicobacter pylori in gastric acidic territory

S Ansari, Y Yamaoka - Helicobacter, 2017 - Wiley Online Library
Background Helicobacter pylori is well adapted to colonize the epithelial surface of the
human gastric mucosa and can cause persistent infections. In order to infect the gastric …

Roles of oxidative stress in stomach disorders

H Suzuki, T Nishizawa, H Tsugawa… - Journal of clinical …, 2011 - jstage.jst.go.jp
抄録 The stomach is a sensitive digestive organ that is susceptible and exposed to
exogenous pathogens from the diet. In response to such pathogens, the stomach induces …

The diverse antioxidant systems of Helicobacter pylori

G Wang, P Alamuri, RJ Maier - Molecular microbiology, 2006 - Wiley Online Library
The gastric pathogen Helicobacter pylori induces a strong inflammatory host response, yet
the bacterium maintains long‐term persistence in the host. H. pylori combats oxidative stress …

The physiological role of ferritin-like compounds in bacteria

JL Smith - Critical reviews in microbiology, 2004 - Taylor & Francis
Iron, as the ferrous or ferric ion, is essential for the life processes of all eukaryotes and most
prokaryotes; however, the element is toxic when in excess of that needed for cellular …

Adaptive value of sex in microbial pathogens

RE Michod, H Bernstein, AM Nedelcu - Infection, Genetics and Evolution, 2008 - Elsevier
Explaining the adaptive value of sex is one of the great outstanding problems in biology. The
challenge comes from the difficulty in identifying the benefits provided by sex, which must …

The Iron-Binding Protein Dps Confers Hydrogen Peroxide Stress Resistance to Campylobacter jejuni

T Ishikawa, Y Mizunoe, S Kawabata… - Journal of …, 2003 - Am Soc Microbiol
We identified and characterized the iron-binding protein Dps from Campylobacter jejuni.
Electron microscopic analysis of this protein revealed a spherical structure of 8.5 nm in …

The antioxidant protein alkylhydroperoxide reductase of Helicobacter pylori switches from a peroxide reductase to a molecular chaperone function

MH Chuang, MS Wu, WL Lo, JT Lin… - Proceedings of the …, 2006 - National Acad Sciences
Helicobacter pylori, an oxygen-sensitive microaerophilic bacterium, contains many
antioxidant proteins, among which alkylhydroperoxide reductase (AhpC) is the most …

The Lyme disease agent Borrelia burgdorferi requires BB0690, a Dps homologue, to persist within ticks

X Li, U Pal, N Ramamoorthi, X Liu… - Molecular …, 2007 - Wiley Online Library
Borrelia burgdorferi survives in an enzootic cycle, and Dps proteins protect DNA against
damage during starvation or oxidative stress. The role of a Dps homologue encoded by …