Chemistry, traditionally being the science of synthesis and structural manipulations of
molecules, has gradually undertaken the more challenging task of biology-oriented …

Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Introduction: The copper (I)-catalyzed 1, 3-dipolar cycloaddition of alkynes and azides to
form 1, 2, 3-triazoles is the most popular reaction in click chemistry. This reaction is also near …

Cancer is a class of formidable disease with high degree of mortality. Despite much
progress in chemotherapy, the problem of drug resistance has led to the search for newer …

The action of proteases can be controlled by several mechanisms, including regulation
through gene expression; post-translational modifications, such as glycosylation; zymogen …

The integrins are a family of 24 heterodimeric transmembrane cell surface receptors.
Involvement in cell attachment to the extracellular matrix, motility, and proliferation identifies …

A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted
molecular properties such as enhanced stability or biological activity. It is a very powerful …

Recombinant proteins and cytokines are under broad preclinical and clinical investigation to
promote angiogenesis, but their success is limited by ineffective delivery, lack of long-term …

ABSTRACT A series of poly (ether sulfone)‐based anion exchange membranes (AEMs),
tethering with guanidinium side chains with different spacers, were synthesized via azide …

The Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as" click"
reaction, has become a very popular reaction in the last years. It affords exclusively 1, 4 …