Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that acts on multiple cell
lineages, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils and …

The cytokine TSLP has been shown to be a key factor in maintaining immune homeostasis
and regulating inflammatory responses at mucosal barriers. While the role of TSLP in type 2 …

Mucosal surfaces such as the intestinal tract are continuously exposed to both potential
pathogens and beneficial commensal microorganisms. This creates a requirement for a …

Gene expression profiling of 207 uniformly treated children with high-risk B-progenitor acute
lymphoblastic leukemia revealed 29 of 207 cases (14%) with markedly elevated expression …

The human intestine is colonized by an estimated 100 trillion bacteria. Some of these
bacteria are essential for normal physiology, whereas others have been implicated in the …

INTRODUCTION Obesity and its associated complications are serious global concerns.
Despite growing public health initiatives, obesity rates continue to rise. Thus, there is a …

Originally shown to promote the growth and activation of B cells, thymic stromal
lymphopoietin (TSLP) is now known to have wide-ranging impacts on both hematopoietic …

There is compelling evidence that epithelial cells (ECs) at mucosal surfaces, beyond their
role in creating a physical barrier, are integral components of innate and adaptive immunity …

Intestinal epithelial cells (IECs) produce thymic stromal lymphopoietin (TSLP); however, the
in vivo influence of TSLP–TSLP receptor (TSLPR) interactions on immunity and …

Memory B cells are more heterogeneous than previously thought. Given that B cells play
powerful antibody-independent effector functions, it seems reasonable to assume division of …