Emerging role of bacterial extracellular vesicles in cancer

A Chronopoulos, R Kalluri - Oncogene, 2020 - nature.com
Shedding of microbial extracellular vesicles constitutes a universal mechanism for inter-
kingdom and intra-kingdom communication that is conserved among prokaryotic and …

Gram-positive bacterial extracellular vesicles and their impact on health and disease

Y Liu, KAY Defourny, EJ Smid, T Abee - Frontiers in microbiology, 2018 - frontiersin.org
During recent years it has become increasingly clear that the release of extracellular
vesicles (EVs) is a feature inherent to all cellular life forms. These lipid bilayer-enclosed …

Bystander activation and autoimmunity

Y Pacheco, Y Acosta-Ampudia, DM Monsalve… - Journal of …, 2019 - Elsevier
The interaction over time of genetic, epigenetic and environmental factors (ie, autoimmune
ecology) increases or decreases the liability an individual would have to develop an …

Extracellular vesicles and infectious diseases: new complexity to an old story

JS Schorey, CV Harding - The Journal of clinical …, 2016 - Am Soc Clin Investig
Exosomes and other extracellular microvesicles (ExMVs) have important functions in
intercellular communication and regulation. During the course of infection, these vesicles …

Tuberculosis and the art of macrophage manipulation

S Upadhyay, E Mittal, JA Philips - Pathogens and disease, 2018 - academic.oup.com
Macrophages are first-line responders against microbes. The success of Mycobacterium
tuberculosis (Mtb) rests upon its ability to convert these antimicrobial cells into a permissive …

[HTML][HTML] Role of extracellular vesicles in viral and bacterial infections: pathogenesis, diagnostics, and therapeutics

M Rodrigues, J Fan, C Lyon, M Wan, Y Hu - Theranostics, 2018 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs), or exosomes, are nanovesicles of endocytic origin that carry
host and pathogen-derived protein, nucleic acid, and lipid cargos. They are secreted by …

Extracellular vesicles as delivery vehicles of specific cellular cargo

B Mir, C Goettsch - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs) mediate cell-to-cell communication via the transfer of
biomolecules locally and systemically between organs. It has been elucidated that the …

Exosomes in pathogen infections: a bridge to deliver molecules and link functions

W Zhang, X Jiang, J Bao, Y Wang, H Liu… - Frontiers in …, 2018 - frontiersin.org
Exosomes are extracellular vesicles derived from cell endocytosis which act as transmitters
between cells. They are composed of proteins, lipids, and RNAs through which they …

OMV vaccines and the role of TLR agonists in immune response

F Mancini, O Rossi, F Necchi, F Micoli - International journal of molecular …, 2020 - mdpi.com
Outer Membrane Vesicles (OMVs) are bacterial nanoparticles that are spontaneously
released during growth both in vitro and in vivo by Gram-negative bacteria. They are …

[HTML][HTML] Phenolic glycolipid facilitates mycobacterial escape from microbicidal tissue-resident macrophages

CJ Cambier, SM O'Leary, MP O'Sullivan, J Keane… - Immunity, 2017 - cell.com
Mycobacterium tuberculosis (Mtb) enters the host in aerosol droplets deposited in lung
alveoli, where the bacteria first encounter lung-resident alveolar macrophages. We studied …