Lipopolysaccharide modification in Gram-negative bacteria during chronic infection

RF Maldonado, I Sá-Correia… - FEMS microbiology …, 2016 - academic.oup.com
The Gram-negative bacterial lipopolysaccharide (LPS) is a major component of the outer
membrane that plays a key role in host–pathogen interactions with the innate immune …

pathogenesis of Helicobacter pylori‐induced gastric inflammation

DA Israel, RM Peek - Alimentary pharmacology & therapeutics, 2001 - Wiley Online Library
Helicobacter pylori causes persistent inflammation in the human stomach, yet only a minority
of persons harbouring this organism develop peptic ulcer disease or gastric malignancy. An …

Helicobacter pylori Uses Motility for Initial Colonization and To Attain Robust Infection

KM Ottemann, AC Lowenthal - Infection and immunity, 2002 - Am Soc Microbiol
Helicobacter pylori has been shown to require flagella for infection of the stomach. To
analyze whether flagella themselves or motility is needed by these pathogens, we …

Highly efficient chemoenzymatic synthesis of β1–4-linked galactosides with promiscuous bacterial β1–4-galactosyltransferases

K Lau, V Thon, H Yu, L Ding, Y Chen… - Chemical …, 2010 - pubs.rsc.org
Two bacterial β1–4-galactosyltransferases, NmLgtB and Hp1–4GalT, exhibit promiscuous
and complementary acceptor substrate specificity. They have been used in an efficient one …

Relevance of fucosylation and Lewis antigen expression in the bacterial gastroduodenal pathogen Helicobacter pylori

AP Moran - Carbohydrate research, 2008 - Elsevier
Helicobacter pylori is a prevalent bacterial, gastroduodenal pathogen of humans that can
express Lewis (Le) and related antigens in the O-chains of its surface lipopolysaccharide …

Lewis antigens in Helicobacter pylori: biosynthesis and phase variation

G Wang, Z Ge, DA Rasko, DE Taylor - Molecular microbiology, 2000 - Wiley Online Library
The lipopolysaccharides (LPS) of most Helicobacter pylori strains contain complex
carbohydrates known as Lewis antigens that are structurally related to the human blood …

Lipopolysaccharide Structure and Biosynthesis in Helicobacter pylori

H Li, T Liao, AW Debowski, H Tang, HO Nilsson… - …, 2016 - Wiley Online Library
This review covers the current knowledge and gaps in Helicobacter pylori
lipopolysaccharide (LPS) structure and biosynthesis. H. pylori is a Gram‐negative bacterium …

Why Helicobacter pylori has Lewis antigens

BJ Appelmelk, MA Monteiro, SL Martin, AP Moran… - Trends in …, 2000 - cell.com
In mimicry with human gastric epithelial cells, the lipopolysaccharide of Helicobacter pylori
expresses Lewis blood group antigens. Recent data suggest that molecular mimicry does …

Galectin‐3 binds to Helicobacter pylori O‐antigen: it is upregulated and rapidly secreted by gastric epithelial cells in response to H. pylori adhesion

M Fowler, RJ Thomas, J Atherton… - Cellular …, 2006 - Wiley Online Library
Helicobacter pylori causes gastritis and some infections result in peptic ulceration, gastric
adenocarcinoma or gastric lymphoma. A critical step in the pathogenesis of these diseases …

Sweet impersonators: Molecular mimicry of host glycans by bacteria

H de Jong, MMSM Wösten, T Wennekes - Glycobiology, 2022 - academic.oup.com
All bacteria display surface-exposed glycans that can play an important role in their
interaction with the host and in select cases mimic the glycans found on host cells, an event …