Targeting IGF-1 signaling pathways in gynecologic malignancies
I Bruchim, H Werner - Expert opinion on therapeutic targets, 2013 - Taylor & Francis
Introduction: The signaling pathways of the insulin-like growth factors (IGF) have been
implicated in the etiology of a number of epithelial neoplasms including prostate, breast …
implicated in the etiology of a number of epithelial neoplasms including prostate, breast …
[HTML][HTML] Associations between metabolic syndrome and gynecologic cancer
DY Lee, TS Lee - Obstetrics & Gynecology Science, 2020 - ncbi.nlm.nih.gov
Metabolic syndrome (MetS) is a group of risk factors that causes cardiovascular and diabetic
morbidity and mortality, which is diagnosed by central obesity, dyslipidemia, hyperglycemia …
morbidity and mortality, which is diagnosed by central obesity, dyslipidemia, hyperglycemia …
Metabolic risk factors and cervical cancer in the metabolic syndrome and cancer project (Me–Can)
BACKGROUND: Little is known about the association between metabolic risk factors and
cervical cancer carcinogenesis. MATERIAL AND METHODS: During mean follow-up of …
cervical cancer carcinogenesis. MATERIAL AND METHODS: During mean follow-up of …
[HTML][HTML] Metabolic syndromes responsible for cervical cancer and advancement of nanocarriers for efficient targeted drug delivery-A review
Cervical cancer (CC), the fourth worldwide incessant malignant neoplasia particularly in
women, emerged as a serious public health problem. Metabolic syndrome (MetS) is an …
women, emerged as a serious public health problem. Metabolic syndrome (MetS) is an …
Changes of T lymphocyte subsets in peripheral blood of patients with intermediate and advanced cervical cancer before and after nimotuzumab combined with …
F Teng, G Cui, L Qian, L Zhao - International Archives of Allergy and …, 2023 - karger.com
Introduction: Cervical cancer (CC) is the main malignant tumor of gynecology with high
mortality. This study aimed to explore the changes of T lymphocyte subsets in the peripheral …
mortality. This study aimed to explore the changes of T lymphocyte subsets in the peripheral …
Management of advanced or recurrent cervical cancer: chemotherapy and beyond
LM Elit, H Hirte - Expert review of anticancer therapy, 2014 - Taylor & Francis
Metastatic or recurrent cervical cancer has a survival duration of approximately 12 months.
Thus, we review the outcomes of chemotherapy and/or novel agents for women who present …
Thus, we review the outcomes of chemotherapy and/or novel agents for women who present …
[HTML][HTML] IGF axis and other factors in HPV-related and HPV-unrelated carcinogenesis
JI Durzyńska - Oncology Reports, 2014 - spandidos-publications.com
The insulin-like growth factor (IGF) axis promotes the growth of cells, tissues and organs. IGF-
1 is mainly produced in the liver but is also secreted from local tissues. In the circulation, IGF …
1 is mainly produced in the liver but is also secreted from local tissues. In the circulation, IGF …
The association between bladder cancer and a single nucleotide polymorphism (rs2854744) in the insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) gene
MR Safarinejad, N Shafiei, SH Safarinejad - Archives of toxicology, 2011 - Springer
Insulin-like growth factors (IGF) regulate growth and development and enhance cellular
proliferation. IGF-binding protein-3 (IGFBP-3) inhibits IGF action by competitively binding …
proliferation. IGF-binding protein-3 (IGFBP-3) inhibits IGF action by competitively binding …
Serum Lipids, Insulin-Like Growth Factor Binding Protein-3 and Treatment Outcomes in Women with and without Cervical Lesions in South Western Uganda: A Cohort …
Purpose There is a documented association between cervical cancer and metabolic
syndrome. In this study, we determined the association between lipids, insulin-like growth …
syndrome. In this study, we determined the association between lipids, insulin-like growth …
The IGF axis in HPV associated cancers
A Pickard, J Durzynska, DJ McCance… - … Research/Reviews in …, 2017 - Elsevier
Human papillomaviruses (HPV) infect and replicate in stratified epithelium at cutaneous and
mucosal surfaces. The proliferation and maintenance of keratinocytes, the cells which make …
mucosal surfaces. The proliferation and maintenance of keratinocytes, the cells which make …