[HTML][HTML] Antimicrobial resistance (AMR) in COVID-19 patients: a systematic review and meta-analysis (November 2019–June 2021)

RM Kariyawasam, DA Julien, DC Jelinski… - … Resistance & Infection …, 2022 - Springer
Abstract Background Pneumonia from SARS-CoV-2 is difficult to distinguish from other viral
and bacterial etiologies. Broad-spectrum antimicrobials are frequently prescribed to patients …

[HTML][HTML] Evolution of SARS-CoV-2 variants: implications on immune escape, vaccination, therapeutic and diagnostic strategies

NZ Zabidi, HL Liew, IA Farouk, A Puniyamurti, AJW Yip… - Viruses, 2023 - mdpi.com
The COVID-19 pandemic caused by SARS-CoV-2 is associated with a lower fatality rate
than its SARS and MERS counterparts. However, the rapid evolution of SARS-CoV-2 has …

[HTML][HTML] Severe COVID-19 outcomes in pediatrics: An observational cohort analysis comparing Alpha, Delta, and Omicron variants

A Bahl, N Mielke, S Johnson, A Desai… - The Lancet Regional …, 2023 - thelancet.com
Objective COVID-19 can rarely lead to severe illness in pediatric patients. The aim of this
study was to determine if severe outcomes in pediatric COVID-19 have changed over the …

[HTML][HTML] COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation

MJ Patton, CJ Orihuela, KS Harrod, MAN Bhuiyan… - Critical Care, 2023 - Springer
Background Recent single-center reports have suggested that community-acquired
bacteremic co-infection in the context of Coronavirus disease 2019 (COVID-19) may be an …

[HTML][HTML] Increased use of antibiotics in the intensive care unit during coronavirus disease (COVID-19) pandemic in a Brazilian hospital

ARO Silva, DR Salgado, LPN Lopes… - Frontiers in …, 2021 - frontiersin.org
Background: Microbial drug resistance is one of the biggest public health problems.
Antibiotic consumption is an essential factor for the emergence and spread of multiresistant …

Epidemiology, risk factors and prognosis of ventilator-associated pneumonia during severe COVID-19: Multicenter observational study across 149 European Intensive …

M Garnier, JM Constantin, N Heming, L Camous… - … Critical Care & Pain …, 2023 - Elsevier
Background COVID-19 patients requiring mechanical ventilation are particularly at risk of
developing ventilator-associated pneumonia (VAP). Risk factors and the prognostic impact …

[HTML][HTML] Role of toll-like receptors and nod-like receptors in acute lung infection

J Le, Y Kulatheepan, S Jeyaseelan - Frontiers in Immunology, 2023 - frontiersin.org
The respiratory system exposed to microorganisms continuously, and the pathogenicity of
these microbes not only contingent on their virulence factors, but also the host's immunity. A …

[HTML][HTML] Unique microbial landscape in the human oropharynx during different types of acute respiratory tract infections

H Li, X Wu, H Zeng, B Chang, Y Cui, J Zhang, R Wang… - Microbiome, 2023 - Springer
Background Secondary bacterial infections and pneumonia are major mortality causes of
respiratory viruses, and the disruption of the upper respiratory tract (URT) microbiota is a …

[HTML][HTML] The gut-lung axis in influenza A: the role of gut microbiota in immune balance

G Ou, H Xu, J Wu, S Wang, Y Chen, L Deng… - Frontiers in …, 2023 - frontiersin.org
Influenza A, the most common subtype, induces 3 to 5 million severe infections and 250,000
to 500,000 deaths each year. Vaccination is traditionally considered to be the best way to …

[HTML][HTML] Incidence and clinical outcomes of bacterial superinfections in critically ill patients with COVID-19

SM Yoon, J Lee, SM Lee, HY Lee - Frontiers in medicine, 2023 - frontiersin.org
Background Bacterial superinfection is not uncommon in critically ill patients with
coronavirus disease (COVID-19) pneumonia requiring intensive care unit (ICU) treatment …