The re-emergence of hepatitis E virus in Europe and vaccine development

G Zahmanova, K Takova, V Tonova, T Koynarski… - Viruses, 2023 - mdpi.com
Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. Transmission of
HEV mainly occurs via the fecal-oral route (ingesting contaminated water or food) or by …

Hepatitis a virus and hepatitis E virus as food-and waterborne pathogens—transmission routes and methods for detection in food

K Nemes, S Persson, M Simonsson - Viruses, 2023 - mdpi.com
Foodborne viruses are an important threat to food safety and public health. Globally, there
are approximately 5 million cases of acute viral hepatitis due to hepatitis A virus (HAV) and …

First insight into the seroepidemiology of hepatitis E Virus (HEV) in dogs, cats, horses, cattle, sheep, and goats from Bulgaria

I Tsachev, K Gospodinova, R Pepovich, K Takova… - Viruses, 2023 - mdpi.com
In recent years, hepatitis E virus (HEV) infection has been found to be widespread among
different animal species worldwide. In Bulgaria, high HEV seropositivity was found among …

Seroprevalence of hepatitis E virus infection among blood donors in Bulgaria

M Baymakova, K Terzieva, R Popov, E Grancharova… - Viruses, 2021 - mdpi.com
Hepatitis E virus (HEV) infection is widespread among domestic pigs, industrial swine, and
wild boars in Bulgaria. The aim of the current research was to present the HEV …

Surveillance STUDY of hepatitis E virus (HEV) in domestic and wild ruminants in northwestern Italy

A Palombieri, S Robetto, F Di Profio, V Sarchese… - Animals, 2020 - mdpi.com
Simple Summary Hepatitis E virus (HEV) infection can cause both acute and chronic
hepatitis in humans and represents an emerging public health concern worldwide. In …

Efficient Production of Chimeric Hepatitis B Virus-Like Particles Bearing an Epitope of Hepatitis E Virus Capsid by Transient Expression in Nicotiana benthamiana

G Zahmanova, M Mazalovska, K Takova, V Toneva… - Life, 2021 - mdpi.com
The core antigen of hepatitis B virus (HBcAg) is capable of self-assembly into virus-like
particles (VLPs) when expressed in a number of heterologous systems. Such VLPs are …

Plant-derived recombinant vaccines against zoonotic viruses

G Zahmanova, K Takova, R Valkova, V Toneva… - Life, 2022 - mdpi.com
Emerging and re-emerging zoonotic diseases cause serious illness with billions of cases,
and millions of deaths. The most effective way to restrict the spread of zoonotic viruses …

Seroprevalence of hepatitis E virus infection among wild boars in Western Bulgaria

I Tsachev, M Baymakova, P Marutsov… - Vector-Borne and …, 2021 - liebertpub.com
Scientific evidence indicates that hepatitis E virus (HEV) infection is a zoonotic disease.
Domestic pigs and wild boars are the main animal reservoir for HEV worldwide. The aim of …

Development and optimization of an enzyme immunoassay to detect serum antibodies against the hepatitis E virus in pigs, using plant-derived ORF2 recombinant …

K Takova, T Koynarski, G Minkov, V Toneva… - Vaccines, 2021 - mdpi.com
Hepatitis E is an emerging global disease, mainly transmitted via the fecal–oral route in
developing countries, and in a zoonotic manner in the developed world. Pigs and wild boar …

High Seroprevalence of Hepatitis E Virus Infection among East Balkan Swine (Sus scrofa) in Bulgaria: Preliminary Results

I Tsachev, M Baymakova, R Pepovich, N Palova… - Pathogens, 2020 - mdpi.com
The East Balkan swine (Sus scrofa) is the only aboriginal pig breed in Bulgaria, and it is
indigenous to the eastern part of the country. The aim of the present study was to investigate …