Absence seizures in children and teenagers are generally considered relatively benign
because of their non-convulsive nature and the large incidence of remittance in early …

T-type Ca2+ channels were originally called low-voltage-activated (LVA) channels because
they can be activated by small depolarizations of the plasma membrane. In many neurons …

Although it is well established that low-voltage-activated T-type Ca2+ channels play a key
role in many neurophysiological functions and pathological states, the lack of selective and …

The mammalian family of two-pore domain K+ (K2P) channel proteins are encoded by 15
KCNK genes and subdivided into six subfamilies on the basis of sequence similarities …

Low-voltage activated, T-type calcium channels (T-channels) are expressed in many
developing tissues and may be important in regulating important cellular phenotype …

T-type voltage-gated Ca2+ channels have unique electrophysiological properties, suitable
for generating Ca2+ oscillations and waves and thus controlling the proliferation of various …

Vascular smooth muscle is a major constituent of the blood vessel wall, and its many
functions depend on type and location of the vessel, developmental or pathological state …

Key points Lymph transport is promoted by lymphatic pumping, a robust phasic contractile
activity of the collecting lymphatic vessels. This contractile function, critical for tissue fluid …

The spontaneous contractions of collecting lymphatic vessels provide an essential
propulsive force to return lymph centrally. These contractions are driven by an intrinsic …

The role of T-type calcium currents is rarely considered in the extensive literature covering
the mechanisms of long-term synaptic plasticity. This situation reflects the lack of suitable T …