Osteoporosis and the ageing skeleton

TJ Aspray, TR Hill - Biochemistry and cell biology of ageing: Part II clinical …, 2019 - Springer
Osteoporosis is a “skeletal disorder characterized by compromised bone strength
predisposing a person to an increased risk of fracture” which, in light of demographic …

Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan

L Vandenput, H Johansson, EV McCloskey… - Osteoporosis …, 2022 - Springer
We describe the collection of cohorts together with the analysis plan for an update of the
fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource …

A systematic review of intervention thresholds based on FRAX: a report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis …

JA Kanis, NC Harvey, C Cooper, H Johansson… - Archives of …, 2016 - Springer
This systematic review identified assessment guidelines for osteoporosis that incorporate
FRAX. The rationale for intervention thresholds is given in a minority of papers. Intervention …

Risk assessment tools for osteoporosis and fractures in 2022

JJ Carey, PCH Wu, D Bergin - Best Practice & Research Clinical …, 2022 - Elsevier
Osteoporosis is one of the frequently encountered non-communicable diseases in the world
today. Several hundred million people have osteoporosis, with many more at risk. The …

2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary

A Papaioannou, S Morin, AM Cheung, S Atkinson… - Cmaj, 2010 - Can Med Assoc
Since the publication of the Osteoporosis Canada guide-lines in 2002, there has been a
paradigm shift in the prevention and treatment of osteoporosis and fractures. 1, 2 The focus …

Meta-analysis of diabetes mellitus-associated differences in bone structure assessed by high-resolution peripheral quantitative computed tomography

M Walle, DE Whittier, M Frost, R Müller… - Current osteoporosis …, 2022 - Springer
Abstract Purpose of Review Diabetes mellitus is defined by elevated blood glucose levels
caused by changes in glucose metabolism and, according to its pathogenesis, is classified …

Relationship among body fat percentage, body mass index, and all-cause mortality

R Padwal, SR Majumdar, WD Leslie - Annals of internal medicine, 2016 - acpjournals.org
TO THE EDITOR: Financial incentives can reinforce consumer behavior (for example,
offering money back for using a specific credit card), and these procedures are gaining …

A decade of FRAX: how has it changed the management of osteoporosis?

JA Kanis, NC Harvey, H Johansson, E Liu… - Aging clinical and …, 2020 - Springer
The fracture risk assessment tool, FRAX®, was released in 2008 and provides country-
specific algorithms for estimating individualized 10-year probability of hip and major …

FRAX underestimates fracture risk in patients with diabetes

LM Giangregorio, WD Leslie, LM Lix… - Journal of bone and …, 2012 - academic.oup.com
The study objective was to determine whether diabetes is a risk factor for incident hip or
major osteoporotic fractures independent of the WHO fracture risk assessment tool (FRAX) …

Screening to prevent osteoporotic fractures: updated evidence report and systematic review for the US Preventive Services Task Force

M Viswanathan, S Reddy, N Berkman, K Cullen… - Jama, 2018 - jamanetwork.com
Importance Osteoporotic fractures cause significant morbidity and mortality. Objective To
update the evidence on screening and treatment to prevent osteoporotic fractures for the US …