Tissue kallikrein (KLK1) and kallikrein-related peptidases (KLK2–15) comprise a family of 15
highly conserved secreted serine proteases with similar structural characteristics and a wide …

Early diagnosis of cancer and early detection of relapse following surgery are critical for the
effective treatment of the disease and for a positive clinical outcome. Identification of novel …

Background: Tissue kallikrein and kallikrein-related peptidases (KLKs) compose a family of
serine endopeptidases with much clinical interest in oncology, as their potential as …

The kallikrein family comprises tissue kallikrein and 14 kallikrein-related peptidases (KLKs)
recognized as a subgroup of secreted trypsin-or chymotrypsin-like serine proteases. KLKs …

Given that 1.3 million new cases of breast cancer are universally registered among women
and approximately 36% of the patients die annually, the revelation of new predictive markers …

Introduction Human kallikrein-related peptidases (KLKs) represent a subgroup of 15 serine
endopeptidases involved in various physiological processes and pathologies, including …

Background Kallikrein-related peptidase 5 (KLK5) is a secreted trypsin-like protease of the
KLK family, encoded by the KLK5 gene. KLK5 has been found to cleave various …

Abstract Kallikrein-related peptidase 14 (KLK14) is a member of the tissue kallikrein family of
proteases, which are associated with the pathogenesis of malignant tumors and are …

Purpose Gene expression of a variety of the 15 members of the KLK serine protease family
is dysregulated in ovarian cancer. We aimed at determining the clinical relevance of KLK13 …

Objectives As kallikrein-related peptidase 12 (KLK12) has been implicated in the cancer
progression and alternative splicing plays significant role in this disease, the aim of this …