Reactive oxygen species (ROS) are produced by both enzymatic and non-enzymatic
systems within eukaryotic cells and play important roles in cellular physiology and …

The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …

Introduction 3. Reactive oxygen species in tumor growth and cellular survival 4. Reactive
oxygen species in cell motility and metastasis formation 5. Generation of reactive oxygen …

Extracellular stimuli elicit a variety of responses, such as cell proliferation and differentiation,
through the cellular signalling system. Binding of growth factors to the respective receptor …

Reactive oxygen species (ROS) are known mediators of intracellular signal cascades.
Excessive production of ROS may lead to oxidative stress, loss of cell function, and cell …

Reactive oxygen species (ROS) are generated at sites of inflammation and injury, and at low
levels, ROS can function as signaling molecules participating as signaling intermediates in …

As a cornerstone of the innate immune response, neutrophils are the archetypical
phagocytic cell; they actively seek out, ingest, and destroy pathogenic microorganisms. To …

Redox (oxidation-reduction) reactions regulate signal transduction. Oxidants such as
superoxide, hydrogen peroxide, hydroxyl radicals, and lipid hydroperoxides (ie, reactive …

Abstract Although superoxide anions (O2.-) and H2O2 are generally considered to be toxic
by-products of respiration, recent evidence suggests that the production of these reactive …

Emerging evidence indicates that reactive oxygen species, especially superoxide and
hydrogen peroxide, are important signaling molecules in cardiovascular cells. Their …