Aberrant Cyclin D1 splicing in cancer: from molecular mechanism to therapeutic modulation

J Wang, W Su, T Zhang, S Zhang, H Lei, F Ma… - Cell Death & …, 2023 - nature.com
Abstract Cyclin D1 (CCND1), a crucial mediator of cell cycle progression, possesses many
mutation types with different mutation frequencies in human cancers. The G870A mutation is …

The Triple Crown: NO, CO, and H2S in cancer cell biology

PP Oza, K Kashfi - Pharmacology & Therapeutics, 2023 - Elsevier
Nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S) are three
endogenously produced gases with important functions in the vasculature, immune defense …

Prognostic biomarkers of cell proliferation in colorectal cancer (CRC): from immunohistochemistry to molecular biology techniques

A Kasprzak - Cancers, 2023 - mdpi.com
Simple Summary This review aims to shed light on the proliferative markers important in the
everyday clinical management of colorectal cancer (CRC), ranging from simple methods of …

Increased expression of Ki-67 is a poor prognostic marker for colorectal cancer patients: a meta analysis

ZW Luo, MG Zhu, ZQ Zhang, FJ Ye, WH Huang, XZ Luo - BMC cancer, 2019 - Springer
Background The prognostic value of Ki-67 expression in colorectal cancer patients was
controversial. Therefore, this meta analysis was conducted to ascertain the prognostic value …

Evaluation of enterotoxigenic Bacteroides fragilis correlation with the expression of cellular signaling pathway genes in Iranian patients with colorectal cancer

L Dadgar-Zankbar, A Shariati, N Bostanghadiri… - Infectious Agents and …, 2023 - Springer
Background Colorectal cancer (CRC) is one of the most common cancers all over the world,
and dysbiosis in the gut microbiota may play a role in colorectal carcinogenesis. Bacteroides …

The impact of coffee and its selected bioactive compounds on the development and progression of colorectal cancer in vivo and in vitro

RJ Bułdak, T Hejmo, M Osowski, Ł Bułdak, M Kukla… - Molecules, 2018 - mdpi.com
Coffee is one of the most popular beverages worldwide. Coffee contains bioactive
compounds that affect the human body such as caffeine, caffeic acid, chlorogenic acids …

Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark

HJ Eo, JH Park, GH Park, MH Lee, JR Lee… - … and alternative medicine, 2014 - Springer
Background Root bark of mulberry (Morus alba L.) has been used in herbal medicine as anti-
phlogistic, liver protective, kidney protective, hypotensive, diuretic, anti-cough and analgesic …

Prognostic significance of cyclin D1 expression in colorectal cancer: a meta-analysis of observational studies

Y Li, J Wei, C Xu, Z Zhao, T You - PloS one, 2014 - journals.plos.org
Objective Cyclin D1 plays a vital role in cancer cell cycle progression and is overexpressed
in many human cancers, including colorectal cancer (CRC). However, the prognostic value …

Ultrasensitive and selective detection of a prognostic indicator in early‐stage cancer using graphene oxide and carbon nanotubes

X Wang, C Wang, K Qu, Y Song, J Ren… - Advanced Functional …, 2010 - Wiley Online Library
Cyclin A2 is a prognostic indicator in early‐stage cancer. However, since most of peptide‐
protein bindings do not produce an easily measurable output signal, this severely hinders …

[HTML][HTML] CCND1/CyclinD1 status in metastasizing bladder cancer: a prognosticator and predictor of chemotherapeutic response

R Seiler, GN Thalmann, D Rotzer, A Perren… - Modern pathology, 2014 - Elsevier
The CCND1 gene encodes the protein CyclinD1, which is an important promoter of the cell
cycle and a prognostic and predictive factor in different cancers. CCND1 is amplified to a …