▪ Abstract The separation of sister chromatids at the metaphase to anaphase transition is
one of the most dramatic of all cellular events and is a crucial aspect of all sexual and …

▪ Abstract Completion of the cell cycle requires the temporal and spatial coordination of
chromosome segregation with mitotic spindle disassembly and cytokinesis. In budding …

In budding yeast, the phosphatase Cdc14, a key regulator of exit from mitosis, is released
from its inhibitor Cfi1/Net1 in the nucleolus during anaphase. A signaling cascade, known as …

Meiosis is a specialized cell division program that is essential for sexual reproduction. The
two meiotic divisions reduce chromosome number by half, typically generating haploid …

The orderly reduction in chromosome number that occurs during meiosis depends on two
aspects of chromosome behavior specific to the first meiotic division. These are the retention …

We have characterized a new gene, SWI1, involved in sister chromatid cohesion during both
male and female meiosis in Arabidopsis thaliana. A first allele, swi1. 1, was obtained as a T …

Anaphase is the stage of the cell cycle when the duplicated genome is separated to
opposite poles of the cell. The irreversible nature of this event confers a unique burden on …

Throughout oocyte maturation, and subsequently during the first mitotic cell cycle, the MAP
kinase cascade and cyclin-B–Cdc2 kinase are associated with the control of cell cycle …

▪ Abstract The replicated copies of each chromosome, the sister chromatids, are attached
prior to their segregation in mitosis and meiosis. This association or cohesion is critical for …

During meiosis, DNA replication is followed by two consecutive rounds of chromosome
segregation. Cells lacking the protein phosphatase CDC14 or its regulators, SPO12 and …