Epstein Barr virus: development of vaccines and immune cell therapy for EBV-associated diseases

X Cui, CM Snapper - Frontiers in Immunology, 2021 - frontiersin.org
Epstein-Barr virus (EBV) is the first human tumor virus discovered and is strongly implicated
in the etiology of multiple lymphoid and epithelial cancers. Each year EBV associated …

[HTML][HTML] Epstein Barr virus associated lymphomas and epithelia cancers in humans

R Ayee, MEO Ofori, E Wright, O Quaye - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Epstein Barr virus (EBV) is a cosmopolitan oncogenic virus, infecting about 90% of the
world's population and it is associated to tumors originating from both epithelia and …

The interplay between Epstein–Barr virus and B lymphocytes: implications for infection, immunity, and disease

OL Hatton, A Harris-Arnold, S Schaffert, SM Krams… - Immunologic …, 2014 - Springer
Human B cells are the primary targets of Epstein–Barr virus (EBV) infection. In most cases,
EBV infection is asymptomatic because of a highly effective host immune response, but …

Virus-specific T-cell banks for'off the shelf'adoptive therapy of refractory infections

RJ O'Reilly, S Prockop, AN Hasan, G Koehne… - Bone marrow …, 2016 - nature.com
Adoptive immunotherapy with transplant donor-derived virus-specific T cells has emerged
as a potentially curative approach for the treatment of drug-refractory EBV+ lymphomas as …

Post-transplant lymphoproliferative disorders

VR Dharnidharka, AC Webster, OM Martinez… - Nature reviews Disease …, 2016 - nature.com
Post-transplant lymphoproliferative disorders (PTLDs) are a group of conditions that involve
uncontrolled proliferation of lymphoid cells as a consequence of extrinsic …

Using Epstein-Barr viral load assays to diagnose, monitor, and prevent posttransplant lymphoproliferative disorder

ML Gulley, W Tang - Clinical Microbiology Reviews, 2010 - Am Soc Microbiol
SUMMARY Epstein-Barr virus (EBV) DNA measurement is being incorporated into routine
medical practice to help diagnose, monitor, and predict posttransplant lymphoproliferative …

[HTML][HTML] Epstein-Barr virus and posttransplant lymphoproliferative disorder in solid organ transplantation

UD Allen, JK Preiksaitis… - American journal of …, 2013 - Elsevier
Posttransplant lymphoproliferative disorder (PTLD) is recognized as potentially one of the
most devastating complications of organ transplantation. The Epstein–Barr virus (EBV) …

Epstein-Barr virus–positive posttransplant lymphoproliferative disease after solid organ transplantation: pathogenesis, clinical manifestations, diagnosis, and …

ML Nijland, MJ Kersten, ST Pals… - Transplantation …, 2016 - journals.lww.com
Posttransplant lymphoproliferative disease (PTLD) is a potentially fatal complication after
(solid organ) transplantation, which is highly associated with Epstein-Barr virus (EBV). The …

[HTML][HTML] Comprehensive review of post–organ transplant hematologic cancers

VR Dharnidharka - American Journal of Transplantation, 2018 - Elsevier
A higher risk for a variety of cancers is among the major complications of posttransplantation
immunosuppression. In this part of a continuing series on cancers posttransplantation, this …

Clinical immune‐monitoring strategies for predicting infection risk in solid organ transplantation

M Fernández‐Ruiz, D Kumar… - Clinical & translational …, 2014 - Wiley Online Library
Infectious complications remain a leading cause of morbidity and mortality after solid organ
transplantation (SOT), and largely depend on the net state of immunosuppression achieved …