In the modern scenario, the quinolone scaffold has emerged as a very potent motif
considering its clinical significance. Quinolones possess wide range of pharmacological …

Spontaneous bacterial (SBP) and spontaneous fungal peritonitis (SFP) can be a life-
threatening infection in patients with liver cirrhosis (LC) and ascites. One of the possible …

Background Approximately 2.5% of all hospitalisations in people with liver cirrhosis are for
spontaneous bacterial peritonitis. Spontaneous bacterial peritonitis is associated with …

BACKGROUND The Pringle maneuver [portal triad obstruction (PTO)] provides huge
disturbances during ischemia and even more thereafter in reperfusion. Contrarily, a possible …

Die Leitlinie Komplikationen der Leberzirrhose der Deutschen Gesellschaft für
Gastroenterologie, Verdauungs-und Stoffwechselkrankheiten (DGVS) ersetzt die Leitlinie …

Increased bacterial translocation (BT) across the gut barrier due to greater intestinal
permeability (IP) is seen across a range of conditions, including alcohol-related liver disease …

Due to the restrictions of liver transplantation, complication-guided pharmacological therapy
has become the mainstay of long-term management of cirrhosis. This article aims to provide …

The gut microbiota is a pivotal actor in the maintenance of the balance in the complex
interconnections of hepato-biliary-pancreatic system. It has both metabolic and immunologic …

Acute-on-chronic-liver failure (ACLF) refers to a phenomenon in which patients with chronic
liver disease develop multiple organ failure due to acute exacerbation of underlying liver …

The quinoline scaffold has become an important construction motif for the development of
new drugs. The quinolones and their heteroannulated derivatives have high importance due …