Next-generation sequencing diagnostics of bacteremia in septic patients

S Grumaz, P Stevens, C Grumaz, SO Decker… - Genome medicine, 2016 - Springer
Background Bloodstream infections remain one of the major challenges in intensive care
units, leading to sepsis or even septic shock in many cases. Due to the lack of timely …

Lessons of war: Combat-related injury infections during the Vietnam War and Operation Iraqi and Enduring Freedom

DM Blyth, HC Yun, DR Tribble… - Journal of Trauma and …, 2015 - journals.lww.com
In more than a decade of war, numerous advancements have been made to improve overall
combat-related mortality. Battlefield case-fatality rates (CFRs) have declined steadily …

Infections in burn patients

JL Kiley, DG Greenhalgh - Surgical Clinics, 2023 - surgical.theclinics.com
Infections are the leading cause of mortality in burn patients who survive initial resuscitation
1, 2 and present diagnostic and therapeutic challenges. 3 Here, the authors discuss the role …

Generating and reversing chronic wounds in diabetic mice by manipulating wound redox parameters

S Dhall, DC Do, M Garcia, J Kim… - Journal of diabetes …, 2014 - Wiley Online Library
By 2025, more than 500 M people worldwide will suffer from diabetes; 125 M will develop
foot ulcer (s) and 20 M will undergo an amputation, creating a major health problem …

A thermosensitive hydrogel formulation of phage and colistin combination for the management of multidrug-resistant Acinetobacter baumannii wound infections

S Mukhopadhyay, KKW To, Y Liu, C Bai… - Biomaterials …, 2024 - pubs.rsc.org
Chronic skin wounds are often associated with multidrug-resistant bacteria, impeding the
healing process. Bacteriophage (phage) therapy has been revitalized as a promising …

Molecular evidence of viral DNA in non-small cell lung cancer and non-neoplastic lung

LA Robinson, CJ Jaing, C Pierce Campbell… - British journal of …, 2016 - nature.com
Background: Although∼ 20% of human cancers are caused by microorganisms, only
suspicion exists for a microbial cause of lung cancer. Potential infectious agents were …

Next-generation sequencing diagnostics of bacteremia in sepsis (Next GeneSiS-Trial): study protocol of a prospective, observational, noninterventional, multicenter …

T Brenner, SO Decker, S Grumaz, P Stevens… - Medicine, 2018 - journals.lww.com
Background: Sepsis remains a major challenge, even in modern intensive care medicine.
The identification of the causative pathogen is crucial for an early optimization of the …

Antimicrobial analysis of honey against Staphylococcus aureus isolates from wound, ADMET properties of its bioactive compounds and in-silico evaluation against …

UO Edet, EN Mbim, E Ezeani, OU Henshaw… - … medicine and therapies, 2023 - Springer
Background One of the main challenges of wound healing is infection with multi-drug
resistant (MDR) bacteria such as Staphylococcus aureus. The spectrum of antibiotics used …

The impact of armed conflict on the development and global spread of antibiotic resistance: a systematic review

G Granata, E Petersen, A Capone, D Donati… - Clinical Microbiology …, 2024 - Elsevier
Background Scant data are available on the link between armed conflicts and the
development and spread of antimicrobial resistance. Objectives We perfomed a systematic …

Heterotopic ossification and lessons learned from fifteen years at war: a review of therapy, novel research, and future directions for military and civilian orthopaedic …

BW Hoyt, GJ Pavey, BK Potter, JA Forsberg - Bone, 2018 - Elsevier
Heterotopic ossification, the formation of bone in soft tissues, is a common complication of
the high-energy extremity trauma sustained in modern armed conflict. In the past 15 years …