In situ hybridization (ISH) is a technique by which specific nucleotide sequences are
identified in cells or tissue sections. These may be endogenous, bacterial or viral, DNA or …

Clonal chromosome abnormalities can be detected in approximately 50% of patients with
chronic lymphocytic leukemia (CLL). The most common changes are trisomy 12, followed by …

Fluorescence in situ hybridization (FISH) with a chromosome 12 specific alpha-centromeric
probe was performed on interphase cells from 183 patients with B-cell chronic lymphocytic …

Cytogenetic studies (CG) of 475 chronic lymphocytic leukemia (CLL) cases showed trisomy
12 in 6.1% or 26% of patients with abnormal karyotypes. Fluorescence in situ hybridization …

Immunophenotypic studies, fluorescence in situ hybridization (FISH) and conventional
karyotyping were used to define the clinicobiological significance of 14q32 translocations …

In chronic B-cell leukemias, fluorescence in situ hybridization has greatly improved the
ability to detect certain chromosomal aberrations, as cells in all phases of the cell cycle are …

Conventional chromosome analysis (CCA) and interphase fluorescence in situ hybridization
(FISH) was performed in 42 patients with mantle-cell lymphoma (MCL), with BCL1 …

Trisomy 3 represents the most frequent and consistent chromosomal abnormality
characterizing the recently defined entity marginal zone B‐cell lymphoma (MZBCL). By …

The incidence of trisomy 12 was studied by conventional chromosome analysis in 111
patients referred as B‐cell chronic lymphocytic leukaemia (B‐CLL). Fluorescent in situ …

Subdivision of CLL into typical and atypical subtypes, as proposed by the FAB group in
1989, is not yet widely accepted and its clinical significance is still debated. In recent years …