Molecular basis of differences among statins and a comparison with antioxidant vitamins

RP Mason - The American journal of cardiology, 2006 - Elsevier
Although all statin drugs lower levels of circulating low-density lipoprotein cholesterol by
inhibiting 3-hydroxy-3-methylglutaryl coenzyme A, molecular differences among statins …

Cardiovascular pleiotropic effects of statins and new onset diabetes: is there a common link: do we need to evaluate the role of KATP channels?

D Sehra, S Sehra, ST Sehra - Expert Opinion on Drug Safety, 2017 - Taylor & Francis
Introduction: Statins are considered the main stay of treatment in the prevention of cardio-
vascular morbidity and mortality. They have multiple pleiotropic effects, like stabilization of …

Prevalence of tinnitus in patients withhypertension and the impact of different anti hypertensive drugs on the incidence of tinnitus: A prospective, single-blind …

C Borghi, C Brandolini, MG Prandin, A Dormi… - Current therapeutic …, 2005 - Elsevier
BACKGROUND:: Tinnitus is a common symptom in audiology and neurologypatients.
Controversial data have been reported in the literature about the prevalence of tinnitus in …

Resveratrol ameliorates the cyclosporine-induced vascular and renal impairments: possible impact of the modulation of renin–angiotensin system

S Bekpinar, E Karaca, S Yamakoğlu… - Canadian journal of …, 2019 - cdnsciencepub.com
Cyclosporine, an immunosuppressive drug, exhibits a toxic effect on renal and vascular
systems. The present study investigated whether resveratrol treatment alleviates renal and …

Effects of Crataegus microphylla on Vascular Dysfunction in Streptozotocin‐induced Diabetic Rats

G Topal, E Koç, Ç Karaca, T Altuğ, B Ergin… - Phytotherapy …, 2013 - Wiley Online Library
Vascular dysfunction plays a key role in the pathogenesis of diabetic vascular disease. In
this study, we aimed to investigate whether chronic in vivo treatment of Crataegus …

Skin autofluorescence is associated with endothelial dysfunction in uremic subjects on hemodialysis

CC Wang, YC Wang, GJ Wang, MY Shen, YL Chang… - PloS one, 2016 - journals.plos.org
Background Elevated levels of advanced glycation end products (AGEs) within tissues may
contribute to endothelial dysfunction, an early indicator of atherosclerosis. We aimed to …

Low-dose atorvastatin, losartan, and particularly their combination, provide cardiovascular protection in isolated rat heart and aorta

M Lunder, L Žiberna, M Janić, A Jerin, M Skitek… - Heart and vessels, 2013 - Springer
Statins and angiotensin receptor blockers at therapeutic doses have beneficial
cardiovascular effects, which can be applied for cardiovascular protection. We explored …

The comparison of the relaxant effects of two methoxylated flavones in rat aortic rings

BS Uydeş-Doğan, S Takır, O Özdemir, U Kolak… - Vascular …, 2005 - Elsevier
The vascular effect of salvigenin, a natural flavone, was investigated in comparison with
another flavone, in rat aotic rings. Cumulative addition of their increasing concentrations …

Evaluation of the effects of pioglitazone on perivascular adipose tissue function, properties, and structure in a rat model of type-2 diabetes

E Civelek, EF Karaman, S Özden… - Canadian Journal of …, 2024 - cdnsciencepub.com
Perivascular adipose tissue (PVAT) plays an important role in many physiological and
pathological processes, such as regulation of vascular tone. The aim of this study is to …

Cilostazol enhances atorvastatin-induced vasodilation of female rat aorta during aging

KE Nurullahoğlu-Atalık, S Kutlu, H Solak… - Physiology …, 2017 - akjournals.com
Statins have cholesterol-independent effects including an increased vascular nitric oxide
activity and are commonly used by patients with cardiovascular disease. Such patients …