T cell responses to SARS-CoV-2
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …
challenge in this century. Two years after its emergence, the rapid development and …
Efficacy of a fourth dose of Covid-19 mRNA vaccine against Omicron
A Fourth Dose of mRNA Vaccine in Health Care Workers Health care workers in Israel were
given a fourth dose of BNT162b2 or mRNA-1273 vaccine during a period of omicron-variant …
given a fourth dose of BNT162b2 or mRNA-1273 vaccine during a period of omicron-variant …
The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic
M Hoffmann, N Krüger, S Schulz, A Cossmann… - Cell, 2022 - cell.com
The rapid spread of the SARS-CoV-2 Omicron variant suggests that the virus might become
globally dominant. Further, the high number of mutations in the viral spike protein raised …
globally dominant. Further, the high number of mutations in the viral spike protein raised …
Homologous and heterologous Covid-19 booster vaccinations
RL Atmar, KE Lyke, ME Deming… - … England Journal of …, 2022 - Mass Medical Soc
Background Although the three vaccines against coronavirus disease 2019 (Covid-19) that
have received emergency use authorization in the United States are highly effective …
have received emergency use authorization in the United States are highly effective …
An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …
[HTML][HTML] Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single …
G Zeng, Q Wu, H Pan, M Li, J Yang, L Wang… - The Lancet Infectious …, 2022 - thelancet.com
Background Large-scale vaccination against COVID-19 is being implemented in many
countries with CoronaVac, an inactivated vaccine. We aimed to assess the immune …
countries with CoronaVac, an inactivated vaccine. We aimed to assess the immune …
Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK …
ASV Stuart, RH Shaw, X Liu, M Greenland, PK Aley… - The Lancet, 2022 - thelancet.com
Background Given the importance of flexible use of different COVID-19 vaccines within the
same schedule to facilitate rapid deployment, we studied mixed priming schedules …
same schedule to facilitate rapid deployment, we studied mixed priming schedules …
Immunogenicity and efficacy of heterologous ChAdOx1–BNT162b2 vaccination
B Pozzetto, V Legros, S Djebali, V Barateau, N Guibert… - Nature, 2021 - nature.com
Following severe adverse reactions to the AstraZeneca ChAdOx1-S-nCoV-19 vaccine,,
European health authorities recommended that patients under the age of 55 years who …
European health authorities recommended that patients under the age of 55 years who …
The use of viral vectors in vaccine development
Vaccines represent the single most cost-efficient and equitable way to combat and eradicate
infectious diseases. While traditional licensed vaccines consist of either …
infectious diseases. While traditional licensed vaccines consist of either …