It has been nearly 30 years since Dr. David Barker first highlighted the importance of
prenatal factors in contributing to the developmental origins of adult disease. This concept …

Psychiatric disorders like mood disorders, schizophrenia, or drug addiction affect a sizeable
proportion of the human population and severely compromise quality of life. Therefore …

Background Neurodevelopment is strongly influenced by maternal and early-postnatal diet.
Omega-3 polyunsaturated fatty acids (n-3 PUFA) are vital structural and functional …

The pineal gland hormone melatonin continues to be of considerable interest to biomedical
researchers. Of particular interest is the pattern of secretion of melatonin in relation to sleep …

Depression is a condition in which an individual feels lethargic, irritable, and guilty, has
difficulty and trouble, no enjoyment in life, mood swings, sometimes suicidal ideation and …

Activation of the maternal immune system during pregnancy is a well-established risk factor
for neuropsychiatric disease in the offspring, yet, the underlying mechanisms leading to …

There is a growing recognition of the role played by gut microbes in human health. The
extension of this role, to encompass brain health, has come into focus in recent years …

There is a substantial body of evidence from animal studies implicating polyunsaturated fatty
acids (PUFA) in neuroinflammatory, neurotrophic, and neuroprotective processes in brain …

Dietary n-3 polyunsaturated fatty acids (PUFAs) are critical components of inflammatory
response and memory impairment. However, the mechanisms underlying the sensitizing …

Major depressive disorder (MDD) is a debilitating mental disease, but its underlying
molecular mechanisms remain obscure. Our previously established model of naturally …