Mapping single-cell atlases throughout Metazoa unravels cell type evolution
Comparing single-cell transcriptomic atlases from diverse organisms can elucidate the
origins of cellular diversity and assist the annotation of new cell atlases. Yet, comparison …
origins of cellular diversity and assist the annotation of new cell atlases. Yet, comparison …
[HTML][HTML] New technologies to study helminth development and host-parasite interactions
How parasites develop and survive, and how they stimulate or modulate host immune
responses are important in understanding disease pathology and for the design of new …
responses are important in understanding disease pathology and for the design of new …
A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding
Schistosomiasis is a neglected tropical disease that infects 240 million people. With no
vaccines and only one drug available, new therapeutic targets are needed. The causative …
vaccines and only one drug available, new therapeutic targets are needed. The causative …
SchistoCyte atlas: A single-cell transcriptome resource for adult schistosomes
GR Wendt, ML Reese, JJ Collins III - Trends in parasitology, 2021 - Elsevier
Schistosomes cause untold disease and disability in the developing world. Here, we
introduce SchistoCyte Atlas, a web-based platform for exploring gene expression at single …
introduce SchistoCyte Atlas, a web-based platform for exploring gene expression at single …
Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate
Schistosomes are parasitic flatworms causing one of the most prevalent infectious diseases
from which millions of people are currently suffering. These parasites have high fecundity …
from which millions of people are currently suffering. These parasites have high fecundity …
Single-cell atlas of the first intra-mammalian developmental stage of the human parasite Schistosoma mansoni
Over 250 million people suffer from schistosomiasis, a tropical disease caused by parasitic
flatworms known as schistosomes. Humans become infected by free-swimming, water-borne …
flatworms known as schistosomes. Humans become infected by free-swimming, water-borne …
Self-assembling manifolds in single-cell RNA sequencing data
Single-cell RNA sequencing has spurred the development of computational methods that
enable researchers to classify cell types, delineate developmental trajectories, and measure …
enable researchers to classify cell types, delineate developmental trajectories, and measure …
A single-parasite transcriptional atlas of Toxoplasma Gondii reveals novel control of antigen expression
Toxoplasma gondii, a protozoan parasite, undergoes a complex and poorly understood
developmental process that is critical for establishing a chronic infection in its intermediate …
developmental process that is critical for establishing a chronic infection in its intermediate …
A single-cell atlas of the miracidium larva of Schistosoma mansoni reveals cell types, developmental pathways, and tissue architecture
T Attenborough, KA Rawlinson, CLD Soria, K Ambridge… - Elife, 2024 - elifesciences.org
Schistosoma mansoni is a parasitic flatworm that causes the major neglected tropical
disease schistosomiasis. The miracidium is the first larval stage of the life cycle. It swims and …
disease schistosomiasis. The miracidium is the first larval stage of the life cycle. It swims and …
Daily rhythms in gene expression of the human parasite Schistosoma mansoni
Background The consequences of the earth's daily rotation have led to 24-h biological
rhythms in most organisms. Even some parasites are known to have daily rhythms, which …
rhythms in most organisms. Even some parasites are known to have daily rhythms, which …