A substantial body of literature supports the intuitive notion that a good night's sleep can
facilitate human cognitive performance the next day. Deficits in attention, learning & memory …

Cognitive function is affected by low pressure and hypoxia in high-altitude environments,
and is regulated by altitude and exposure time. With the economic development in the …

Acute hypoxia increases the formation of reactive oxygen species (ROS) in the brain.
However, the effect of reoxygenation, unavoidable to achieve full recovery of the hypoxic …

The structure and dynamics of dendritic spines reflect the strength of synapses, which are
severely affected in different brain diseases. Therefore, understanding the ultra-structure …

The brain requires over one-fifth of the total body oxygen demand for normal functioning. At
high altitude (HA), the lower atmospheric oxygen pressure inevitably challenges the brain …

A critical link between amyloid-beta (Aβ) and hypoxia has been demonstrated in in vitro and
animal studies but has not yet been proven in humans. Obstructive sleep apnea syndrome …

With the advancement of in vivo magnetic resonance imaging (MRI) technique, more
detailed information about the human brain at high altitude (HA) has been revealed. The …

High altitude cerebral edema (HACE) is a severe type of acute mountain sickness (AMS)
that occurs in response to a high altitude hypobaric hypoxic (HH) environment. GM1 …

Withania somnifera root extract has been used traditionally in ayurvedic system of medicine
as a memory enhancer. Present study explores the ameliorative effect of withanolide A, a …

Background Synaptic failure is one of the principal events associated with cognitive
dysfunction in Alzheimer's disease (AD). Preservation of existing synapses and prevention …