Reversed-phase high-performance liquid chromatography (RP-HPLC) is the most popular
chromatographic mode, accounting for more than 90% of all separations. HPLC itself owes …

This review considers some of the difficulties encountered with the analysis of ionised bases
using reversed-phase chromatography, such as detrimental interaction with column silanol …

Reversed-phase (RP) liquid chromatography is an important tool for the characterization of
materials and products in the pharmaceutical industry. Method development is still …

Twenty orthogonality metrics (OMs) derived from convex hull, information theory, fractal
dimension, correlation coefficients, nearest neighbor distances and bin-density techniques …

Separation. selectivity. is. central. to. the. use. of. reversed-phase. chromatography.(RPC)..
Some. examples. of. selectivity. are. illustrated. by. the. three. separations. of. Figure 7.1 …

For more than four decades, scientists and researchers have relied on the Advances in
Chromatography series for the most up-to-date information on a wide range of …

A novel type of stationary phase selectivity classification “triangle” has been developed
based on the Snyder–Dolan (S–D) Hydrophobic-Subtraction Model, wherein the apices of a …

Abstract Comparison and selection of chromatographic columns is an important part of
development as well as validation of analytical methods. Presently there is abundant …

Background Analysis of related substances in pharmaceutical chemicals and multi-
components in traditional Chinese medicines needs bulk of reference substances to identify …

This work reports a chemometrics-assisted high performance liquid chromatography-diode
array detection (HPLC-DAD) strategy to solve varying interfering patterns from different …