Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Structural diversity and biological activities of phloroglucinol derivatives from Hypericum species

H Bridi, G de Carvalho Meirelles, GL von Poser - Phytochemistry, 2018 - Elsevier
Plants of the genus Hypericum (Hypericaceae) are used in folk medicine all over the world,
H. perforatum being the most well-known species. Standardized extracts of this plant are …

Hypericum genus as a natural source for biologically active compounds

GI Caldeira, LP Gouveia, R Serrano, OD Silva - Plants, 2022 - mdpi.com
Hypericum L. genus plants are distributed worldwide, with numerous species identified
throughout all continents, except Antarctica. These plant species are currently used in …

Comparative evaluation of ethyl acetate and n‐Hexane extracts of Cannabis sativa L. leaves for muscle function restoration after peripheral nerve lesion

J Maqbool, H Anwar, A Rasul, A Imran… - Food Science & …, 2023 - Wiley Online Library
Peripheral nerve injuries are one of those complex medical conditions for which a highly
effective first‐line treatment is currently missing. The use of natural compound as medicines …

Green Synthesis of Zingiberis Rhizoma-Based Carbon Dots Attenuates Chemical and Thermal Stimulus Pain in Mice

M Zhang, J Cheng, Y Zhang, H Kong, S Wang… - …, 2020 - Taylor & Francis
Aim: To evaluate the analgesic activity of Zingiberis rhizoma-based carbon dots (ZR-CDs).
Materials & methods: Novel ZR-CDs were prepared via a facile, green pyrolysis method …

The anti-immobility effect of hyperoside on the forced swimming test in rats is mediated by the D2-like receptors activation

JS Haas, ED Stolz, AH Betti, AC Stein… - Planta …, 2011 - thieme-connect.com
The crude extracts of Hypericum species native to South Brazil showed analgesic and
antidepressant-like effects in rodents. The chemical characterization of these species …

Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs

AC Stein, AF Viana, LG Müller, JM Nunes… - Behavioural Brain …, 2012 - Elsevier
In this study we have demonstrated that cyclohexane extract of Hypericum polyanthemum
(POL) and its main phloroglucinol derivative uliginosin B (ULI) present antidepressant-like …

Changes of exhaled volatile organic compounds in postoperative patients undergoing analgesic treatment: a prospective observational study

B Löser, A Grabenschröer, G Pugliese, P Sukul, P Trefz… - Metabolites, 2020 - mdpi.com
Assessment and treatment of postoperative pain can be challenging as objective
examination techniques to detect and quantify pain are lacking. We aimed to investigate …

[HTML][HTML] Stress induction of valuable secondary metabolites in Hypericum polyanthemum acclimatized plants

J de Matos Nunes, LOO Bertodo, LMG Da Rosa… - South African Journal of …, 2014 - Elsevier
Uliginosin B, an antidepressant-like phloroglucinol derivative, three benzopyrans and total
phenolic compounds (TPC) of flowering Hypericum polyanthemum acclimatized plants were …

Endogenous opiates and behavior: 2010

RJ Bodnar - Peptides, 2011 - Elsevier
This paper is the thirty-third consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2010 …