Organoid and Enteroid Modeling of Salmonella Infection

Y Yin, D Zhou - Frontiers in cellular and infection microbiology, 2018 - frontiersin.org
Salmonella are Gram-negative rod-shaped facultative anaerobic bacteria that are comprised
of over 2,000 serovars. They cause gastroenteritis (salmonellosis) with headache …

New Insights on the Early Interaction Between Typhoid and Non-typhoid Salmonella Serovars and the Host Cells

BM Schultz, F Melo-Gonzalez, GA Salazar… - Frontiers in …, 2021 - frontiersin.org
Salmonella enterica is a common source of food and water-borne infections, causing a wide
range of clinical ailments in both human and animal hosts. Immunity to Salmonella involves …

A polyamine acetyltransferase regulates the motility and biofilm formation of Acinetobacter baumannii

J Armalytė, A Čepauskas, G Šakalytė… - Nature …, 2023 - nature.com
Acinetobacter baumannii is a nosocomial pathogen highly resistant to environmental
changes and antimicrobial treatments. Regulation of cellular motility and biofilm formation is …

The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump

FL Short, Q Liu, B Shah, HE Clift, V Naidu, L Li… - Communications …, 2021 - nature.com
Antimicrobial resistance genes, including multidrug efflux pumps, evolved long before the
ubiquitous use of antimicrobials in medicine and infection control. Multidrug efflux pumps …

Comparative genome analysis of the genus Shewanella unravels the association of key genetic traits with known and potential pathogenic lineages

GN Cerbino, GM Traglia, T Ayala Nuñez… - Frontiers in …, 2023 - frontiersin.org
Shewanella spp. are Gram-negative rods widely disseminated in aquatic niches that can
also be found in human-associated environments. In recent years, reports of infections …

Structural and Kinetic Characterization of the SpeG Spermidine/Spermine N-acetyltransferase from Methicillin-Resistant Staphylococcus aureus USA300

S Tsimbalyuk, A Shornikov, P Srivastava, VTB Le… - Cells, 2023 - mdpi.com
Polyamines are simple yet critical molecules with diverse roles in numerous pathogenic and
non-pathogenic organisms. Regulating polyamine concentrations affects the transcription …

Reg4 protects against Salmonella infection-associated intestinal inflammation via adopting a calcium-dependent lectin-like domain

W Wang, Y Wang, Y Lu, J Zhu, X Tian, B Wu… - International …, 2022 - Elsevier
Abstract Salmonella Typhimurium (S. Tm) is Gram-negative flagellated bacteria that can
cause food-borne gastroenteritis and diarrhea in human. Developing efficacious methods …

Spermidine constitutes a key determinant of motility and attachment of Salmonella Typhimurium through a novel regulatory mechanism

AV Nair, A Singh, Y Devasurmutt, SA Rahman… - Microbiological …, 2024 - Elsevier
Spermidine is a poly-cationic molecule belonging to the family of polyamines and is
ubiquitously present in all organisms. Salmonella synthesizes, and harbours specialized …

DNA supercoiling differences in bacteria result from disparate DNA gyrase activation by polyamines

A Duprey, EA Groisman - PLoS Genetics, 2020 - journals.plos.org
DNA supercoiling is essential for all living cells because it controls all processes involving
DNA. In bacteria, global DNA supercoiling results from the opposing activities of …

Critical role of msgA in invasive capacity and intracellular survivability of Salmonella

X Liu, C Wang, W Gai, Z Sun, L Fang… - Applied and …, 2024 - journals.asm.org
Salmonella enterica serovar Typhimurium, which is a common foodborne pathogen, causes
both intestinal and systemic infections in hosts. Salmonella has a complex pathogenic …