Therapeutic cancer vaccines
The clinical benefit of therapeutic cancer vaccines has been established. Whereas
regression of lesions was shown for premalignant lesions caused by HPV, clinical benefit in …
regression of lesions was shown for premalignant lesions caused by HPV, clinical benefit in …
Peptide lipidation–a synthetic strategy to afford peptide based therapeutics
R Kowalczyk, PWR Harris, GM Williams… - Peptides and peptide …, 2017 - Springer
Peptide and protein aberrant lipidation patterns are often involved in many diseases
including cancer and neurological disorders. Peptide lipidation is also a promising strategy …
including cancer and neurological disorders. Peptide lipidation is also a promising strategy …
Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer
The murine MC-38 colorectal cancer model is a commonly used model for cancer with high
mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to …
mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to …
Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication
GG Zom, MM Willems, S Khan, TC van der Sluis… - … for immunotherapy of …, 2018 - Springer
Abstract Background Ligands for the Toll-like receptor (TLR) family can induce activation of
cells of the innate immune system and are widely studied for their potential to enhance …
cells of the innate immune system and are widely studied for their potential to enhance …
M1-derived extracellular vesicles enhance photodynamic therapy and promote immunological memory in preclinical models of colon cancer
Extracellular vesicles (EVs) are promising drug carriers of photosensitizers for photodynamic
therapy (PDT) in cancer treatment, due to their ability to circulate in blood and enter cells …
therapy (PDT) in cancer treatment, due to their ability to circulate in blood and enter cells …
Immune checkpoint inhibition combined with targeted therapy using a novel virus-like drug conjugate induces complete responses in a murine model of local and …
RV Huis in 't Veld, S Ma, RC Kines… - Cancer Immunology …, 2023 - Springer
Metastases remain the leading cause of cancer-related death worldwide. Therefore,
improving the treatment efficacy against such tumors is essential to enhance patient survival …
improving the treatment efficacy against such tumors is essential to enhance patient survival …
Teipp peptide variant and uses thereof
T Van Hall, SH Van Der Burg, K Marjit - US Patent App. 17/780,398, 2023 - Google Patents
Novel peptides, nucleic acid sequences, vectors, modified cells, binding agents and
pharmaceutical compositions are provided that are useful as a medicament, for example in …
pharmaceutical compositions are provided that are useful as a medicament, for example in …
[PDF][PDF] Bulk,. an den
B Hos, MGM Camps - … , E., Ende, TC …, 2020 - scholarlypublications …
The murine MC-38 colorectal cancer model is a commonly used model for cancer with high
mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to …
mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to …
[PDF][PDF] Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer
C van den Ende, D Ruano, K Franken, GMC Janssen… - 2019 - academia.edu
The murine MC-38 colorectal cancer model is a commonly used model for cancer with high
mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to …
mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to …
[PDF][PDF] Combinatorial prospects of nanoparticle mediated immunotherapy of cancer
CG Silva - Biomaterials, 2016 - scholarlypublications …
39 chemo-resistant tumor cells, which go on to drive tumor progression, nano-vehicles could
also be engineered to provoke an appropriate immune response to destroy these cells …
also be engineered to provoke an appropriate immune response to destroy these cells …