Mechanisms of phosphate transport
Over the past 25 years, successive cloning of SLC34A1, SLC34A2 and SLC34A3, which
encode the sodium-dependent inorganic phosphate (Pi) cotransport proteins 2a–2c, has …
encode the sodium-dependent inorganic phosphate (Pi) cotransport proteins 2a–2c, has …
Phosphate transporters of the SLC20 and SLC34 families
IC Forster, N Hernando, J Biber, H Murer - Molecular aspects of medicine, 2013 - Elsevier
Transport of inorganic phosphate (Pi) across the plasma membrane is essential for normal
cellular function. Members of two families of SLC proteins (SLC20 and SLC34) act as Na+ …
cellular function. Members of two families of SLC proteins (SLC20 and SLC34) act as Na+ …
Phosphate transport in epithelial and nonepithelial tissue
N Hernando, K Gagnon, E Lederer - Physiological reviews, 2021 - journals.physiology.org
Phosphate is an essential nutrient for life and is a critical component of bone formation, a
major signaling molecule, and structural component of cell walls. Phosphate is also a …
major signaling molecule, and structural component of cell walls. Phosphate is also a …
Phosphate transporters and their function
J Biber, N Hernando, I Forster - Annual review of physiology, 2013 - annualreviews.org
Plasma phosphate concentration is maintained within a relatively narrow range by control of
renal reabsorption of filtered inorganic phosphate (Pi). Pi reabsorption is a transcellular …
renal reabsorption of filtered inorganic phosphate (Pi). Pi reabsorption is a transcellular …
The SLC34 family of sodium-dependent phosphate transporters
CA Wagner, N Hernando, IC Forster, J Biber - Pflügers Archiv-European …, 2014 - Springer
The SLC34 family of sodium-driven phosphate cotransporters comprises three members:
NaPi-IIa (SLC34A1), NaPi-IIb (SLC34A2), and NaPi-IIc (SLC34A3). These transporters …
NaPi-IIa (SLC34A1), NaPi-IIb (SLC34A2), and NaPi-IIc (SLC34A3). These transporters …
Membrane transport proteins in osteoclasts: the ins and outs
During bone resorption, the osteoclast must sustain an extraordinarily low pH environment,
withstand immense ionic pressures, and coordinate nutrient and waste exchange across its …
withstand immense ionic pressures, and coordinate nutrient and waste exchange across its …
Phosphate transport kinetics and structure-function relationships of SLC34 and SLC20 proteins
IC Forster, N Hernando, J Biber, H Murer - Current topics in membranes, 2012 - Elsevier
Transport of inorganic phosphate (P i) is mediated by proteins belonging to two solute
carrier families (SLC20 and SLC34). Members of both families transport P i using the …
carrier families (SLC20 and SLC34). Members of both families transport P i using the …
Renal phosphate transporters
E Lederer - Current opinion in nephrology and hypertension, 2014 - journals.lww.com
Increasing knowledge of structure function relationships for sodium phosphate
cotransporters, as well as greater appreciation for the complexity of their regulation and role …
cotransporters, as well as greater appreciation for the complexity of their regulation and role …
Physiological sodium concentrations enhance the iodide affinity of the Na+/I− symporter
Abstract The Na+/I− symporter (NIS) mediates active I− transport—the first step in thyroid
hormonogenesis—with a 2Na+: 1I− stoichiometry. NIS-mediated 131I− treatment of thyroid …
hormonogenesis—with a 2Na+: 1I− stoichiometry. NIS-mediated 131I− treatment of thyroid …
Structural fold and binding sites of the human Na+-phosphate cotransporter NaPi-II
C Fenollar-Ferrer, M Patti, T Knöpfel, A Werner… - Biophysical journal, 2014 - cell.com
Phosphate plays essential biological roles and its plasma level in humans requires tight
control to avoid bone loss (insufficiency) or vascular calcification (excess). Intestinal …
control to avoid bone loss (insufficiency) or vascular calcification (excess). Intestinal …