Visual impairment and mental health: unmet needs and treatment options

DL Demmin, SM Silverstein - Clinical ophthalmology, 2020 - Taylor & Francis
Purpose An estimated 2.2 billion people are visually impaired worldwide. Given that age-
related vision loss is a primary cause of vision impairment, this number is projected to rise …

Ocular drug delivery to the retina: current innovations and future perspectives

HM Kim, SJ Woo - Pharmaceutics, 2021 - mdpi.com
Treatment options for retinal diseases, such as neovascular age-related macular
degeneration, diabetic retinopathy, and retinal vascular disorders, have markedly expanded …

Five-year outcomes with anti–vascular endothelial growth factor treatment of neovascular age-related macular degeneration: the comparison of age-related macular …

MG Maguire, DF Martin, G Ying, GJ Jaffe, E Daniel… - Ophthalmology, 2016 - Elsevier
Purpose To describe outcomes 5 years after initiating treatment with bevacizumab or
ranibizumab for neovascular age-related macular degeneration (AMD). Design Cohort …

Nonadherence or nonpersistence to intravitreal injection therapy for neovascular age-related macular degeneration: a mixed-methods systematic review

M Okada, P Mitchell, RP Finger, B Eldem, SJ Talks… - Ophthalmology, 2021 - Elsevier
Topic Systematic review of risk factors for nonadherence and nonpersistence to intravitreal
anti–vascular endothelial growth factor (VEGF) injection therapy for neovascular age-related …

A performance comparison of eight commercially available automatic classifiers for facial affect recognition

D Dupré, EG Krumhuber, D Küster, GJ McKeown - Plos one, 2020 - journals.plos.org
In the wake of rapid advances in automatic affect analysis, commercial automatic classifiers
for facial affect recognition have attracted considerable attention in recent years. While …

[HTML][HTML] Real-world outcomes in patients with neovascular age-related macular degeneration treated with intravitreal vascular endothelial growth factor inhibitors

H Mehta, A Tufail, V Daien, AY Lee, V Nguyen… - Progress in retinal and …, 2018 - Elsevier
Clinical trials identified intravitreal vascular endothelial growth factor inhibitors (anti-VEGF
agents) have the potential to stabilise or even improve visual acuity outcomes in …

Macular morphology and visual acuity in year five of the comparison of age-related macular degeneration treatments trials

GJ Jaffe, GS Ying, CA Toth, E Daniel, JE Grunwald… - Ophthalmology, 2019 - Elsevier
Purpose To evaluate associations of morphologic features with 5-year visual acuity (VA) in
the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Design …

A linkage between angiogenesis and inflammation in neovascular age-related macular degeneration

H Heloterä, K Kaarniranta - Cells, 2022 - mdpi.com
Age-related macular degeneration (AMD) is the leading cause of visual impairment in the
aging population with a limited understanding of its pathogenesis and the number of …

[HTML][HTML] Characterizing new-onset exudation in the randomized phase 2 FILLY trial of complement inhibitor pegcetacoplan for geographic atrophy

CC Wykoff, PJ Rosenfeld, NK Waheed, RP Singh… - Ophthalmology, 2021 - Elsevier
Objectives To evaluate clinical characteristics of eyes in which investigator-determined new-
onset exudative age-related macular degeneration (eAMD) developed during the FILLY trial …

Effect of ranibizumab and aflibercept on best-corrected visual acuity in treat-and-extend for neovascular age-related macular degeneration: a randomized clinical trial

MC Gillies, AP Hunyor, JJ Arnold… - JAMA …, 2019 - jamanetwork.com
Importance To our knowledge, this is the first randomized clinical trial to compare visual
outcomes and injection loads between ranibizumab and aflibercept using an identical treat …