The large GTP ase dynamin is the first protein shown to catalyze membrane fission.
Dynamin and its related proteins are essential to many cell functions, from endocytosis to …

Curving biological membranes establishes the complex architecture of the cell and mediates
membrane traffic to control flux through subcellular compartments. Common molecular …

Cells and organelles are delimited by lipid bilayers in which high deformability is essential to
many cell processes, including motility, endocytosis and cell division. Membrane tension is …

Cells bend their plasma membranes into highly curved forms to interact with the local
environment, but how shape generation is regulated is not fully resolved. Here, we report a …

ESCRT-III is required for lipid membrane remodeling in many cellular processes, from
abscission to viral budding and multi-vesicular body biogenesis. However, how ESCRT-III …

The endosomal sorting complex required for transport-III (ESCRT-III) catalyzes membrane
fission from within membrane necks, a process that is essential for many cellular functions …

During endocytosis, energy is invested to narrow the necks of cargo-containing plasma
membrane invaginations to radii at which the opposing segments spontaneously coalesce …

ABSTRACT A key event in the evolution of eukaryotic cells was the engulfment of an aerobic
bacterium by a larger anaerobic archaebacterium, leading to a close relationship between …

Phagocytosis is a specialized process that enables cellular ingestion and clearance of
microbes, dead cells and tissue debris that are too large for other endocytic routes. As such …

Phospholipids (PLs) with polyunsaturated acyl chains are extremely abundant in a few
specialized cellular organelles such as synaptic vesicles and photoreceptor discs, but their …