Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …

The functional contribution of microglia to normal brain development, healthy brain function,
and neurological disorders is increasingly recognized. However, until recently, the nature of …

Implantable biosensors are valuable scientific tools for basic neuroscience research and
clinical applications. Neurotechnologies provide direct readouts of neurological signal and …

Exercise interventions in individuals with Parkinson's disease incorporate goal-based motor
skill training to engage cognitive circuitry important in motor learning. With this exercise …

Microglia were first identified over a century ago, but our knowledge about their ontogeny
and functions has significantly expanded only recently. Microglia colonize the central …

Microglia were recently shown to play unexpected roles in normal brain development and
adult physiology. This has begun to dramatically change our view of these resident …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease. HD
patients present with movement disorders, behavioral and psychiatric symptoms and …

The brain, endocrine, and immune systems are inextricably linked. Immune molecules have
a powerful impact on neuroendocrine function, including hormone–behavior interactions …

Although microglial activation is associated with all CNS disorders, many of which are
sexually dimorphic or age‐dependent, little is known about whether microglial basal gene …

Early disruptions to neurodevelopment are highly relevant to understanding both psychiatric
risk and underlying pathophysiology that can be targeted by new treatments. Much …