Progress on the detoxification of aflatoxin B1 using natural anti-oxidants

X Wang, T Wang, E Nepovimova, M Long, W Wu… - Food and Chemical …, 2022 - Elsevier
Aflatoxins are toxic secondary metabolites produced by Aspergillus fungi. The most toxic
among them is Aflatoxin B1 (AFB1) which is known to have genotoxic, immunotoxic …

Role of food-derived antioxidants against cisplatin induced-nephrotoxicity

T Gómez-Sierra, D Eugenio-Pérez… - Food and Chemical …, 2018 - Elsevier
Cancer is a relevant public health problem that represents the second leading cause of
global death. In this regard, cisplatin is a highly effective antineoplastic drug used in …

Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Citrus reticulata Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide …

AM Ali, MA Gabbar, SM Abdel-Twab… - Oxidative medicine …, 2020 - Wiley Online Library
This study is aimed at assessing the antihyperglycemic, antihyperlipidemic, and antioxidant
effects of Citrus reticulata (C. reticulata) fruit peel hydroethanolic extract and two flavonoids …

Therapeutic detoxification of quercetin for aflatoxin B1-related toxicity: Roles of oxidative stress, inflammation, and metabolic enzymes

C Dai, G Sharma, G Liu, J Shen, B Shao, Z Hao - Environmental Pollution, 2024 - Elsevier
Aflatoxins (AFTs), a type of mycotoxin mainly produced by Aspergillus parasiticus and
Aspergillus flavus, could be detected in food, feed, Chinese herbal medicine, grain crops …

Modulating impacts of quercetin/sitagliptin combination on streptozotocin-induced diabetes mellitus in rats

HE Eitah, YA Maklad, NF Abdelkader… - Toxicology and applied …, 2019 - Elsevier
Background Since many diabetic patients require combination therapy, the use of herbal
remedies with anti-diabetic activity represents a vital option in diabetes mellitus (DM) …

[HTML][HTML] Acute aflatoxin B1–Induced hepatotoxicity alters gene expression and disrupts lipid and lipoprotein metabolism in rats

OA Rotimi, SO Rotimi, CU Duru, OJ Ebebeinwe… - Toxicology reports, 2017 - Elsevier
In this study, alterations in lipid metabolism associated with acute aflatoxin B1 (AFB1)
induced hepatotoxicity and gene expression changes underlying these effects were …

Evaluation of neuroprotective effects of quercetin against aflatoxin B1-intoxicated mice

E Gugliandolo, AF Peritore, R D'Amico, P Licata… - Animals, 2020 - mdpi.com
Simple Summary Aflatoxin B1 (AFB1) is a mycotoxin commonly present in feed,
characterized by several toxic effects. AFB1 has been described as being responsible for …

Contamination of aflatoxins induces severe hepatotoxicity through multiple mechanisms

Z Hua, R Liu, Y Chen, G Liu, C Li, Y Song… - Frontiers in …, 2021 - frontiersin.org
Aflatoxins (AFs) are commonly contaminating mycotoxins in foods and medicinal materials.
Since they were first discovered to cause “turkey X” disease in the United Kingdom in the …

Ameliorative effects of camel milk and silymarin upon aflatoxin B1 induced hepatic injury in rats

NH Hassaneen, SA Hemeda, AF El Nahas, SE Fadl… - Scientific Reports, 2023 - nature.com
Abstract Aflatoxin B1 (AFB1) poses a major risk to both human and animal health because it
contaminates food, feed, and grains. These dangerous effects can be mitigated using …

Hepatoprotective and antioxidant activity of quercetin loaded chitosan/alginate particles in vitro and in vivo in a model of paracetamol-induced toxicity

V Tzankova, D Aluani, M Kondeva-Burdina… - Biomedicine & …, 2017 - Elsevier
The toxic liver impairment caused by free radical injury or excessive reactive oxigen species
(ROS) formation could be effectivelly attenuated by natural antioxidants. The present study …