Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …
The implications of categorical and category-free mixed selectivity on representational geometries
The firing rates of individual neurons displaying mixed selectivity are modulated by multiple
task variables. When mixed selectivity is nonlinear, it confers an advantage by generating a …
task variables. When mixed selectivity is nonlinear, it confers an advantage by generating a …
Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum suppresses interaction with familiar mice
NS de León Reyes, PS Díaz, R Nogueira, A Ruiz-Pino… - Cell, 2023 - cell.com
Social preference, the decision to interact with one member of the same species over
another, is critical to optimize social interactions. Thus, adult rodents favor interacting with …
another, is critical to optimize social interactions. Thus, adult rodents favor interacting with …
Abstract representations emerge naturally in neural networks trained to perform multiple tasks
WJ Johnston, S Fusi - Nature Communications, 2023 - nature.com
Humans and other animals demonstrate a remarkable ability to generalize knowledge
across distinct contexts and objects during natural behavior. We posit that this ability to …
across distinct contexts and objects during natural behavior. We posit that this ability to …
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off
When choosing between options, we must associate their values with the actions needed to
select them. We hypothesize that the brain solves this binding problem through neural …
select them. We hypothesize that the brain solves this binding problem through neural …
The geometry of cortical representations of touch in rodents
Neurons often encode highly heterogeneous non-linear functions of multiple task variables,
a signature of a high-dimensional geometry. We studied the representational geometry in …
a signature of a high-dimensional geometry. We studied the representational geometry in …
CA2 orchestrates hippocampal network dynamics
A Oliva, A Fernandez‐Ruiz, LA Karaba - Hippocampus, 2023 - Wiley Online Library
The hippocampus is composed of various subregions: CA1, CA2, CA3, and the dentate
gyrus (DG). Despite the abundant hippocampal research literature, until recently, CA2 …
gyrus (DG). Despite the abundant hippocampal research literature, until recently, CA2 …
[HTML][HTML] Symmetry-based representations for artificial and biological general intelligence
Biological intelligence is remarkable in its ability to produce complex behaviour in many
diverse situations through data efficient, generalisable and transferable skill acquisition. It is …
diverse situations through data efficient, generalisable and transferable skill acquisition. It is …
Silencing hippocampal CA2 reduces behavioral flexibility in spatial learning
The hippocampus is a key structure involved in learning and remembering spatial
information. However, the extent to which hippocampal region CA2 is involved in these …
information. However, the extent to which hippocampal region CA2 is involved in these …
A neural mechanism for discriminating social threat from social safety
P Kassraian, SK Bigler, DM Gilly, N Shrotri… - BioRxiv, 2023 - biorxiv.org
Adaptive social behavior enables an animal to distinguish threat-associated from safety-
associated conspecifics. Failure to make this distinction may lead to social withdrawal and …
associated conspecifics. Failure to make this distinction may lead to social withdrawal and …