Methylation of riboses at 2′-OH group is one of the most common RNA modifications found
in number of cellular RNAs from almost any species which belong to all three life domains …

Structural biology studies of archaeal and yeast box C/D ribonucleoprotein particles (RNPs)
reveal a surprisingly wide range of forms. If form ever follows function, the different structures …

2′-O-methylation is one of the most prevalent RNA modifications found in different RNA
types. However, the identities of enzymes participating in the transfer of methyl groups are …

RNA 2′ O-methylation is a 'self'epitranscriptomic modification allowing discrimination
between host and pathogen. Indeed, human immunodeficiency virus 1 (HIV-1) induces 2 …

The high conservation of nucleotides of the T-loop, including their chemical identity, are
hallmarks of tRNAs from organisms belonging to the three Domains of Life. These structural …

Fibrillarin is a highly conserved nucleolar methyltransferase responsible for ribosomal RNA
methylation across evolution from Archaea to humans. It has been reported that fibrillarin is …

Post-transcriptional modifications fulfill many important roles during ribosomal RNA
maturation in all three domains of life. Ribose 2'-O-methylations constitute the most …

Paper I: Ramachandran, S., Krogh, N., Jørgensen, TE, Johansen, SD, Nielsen, H. & Babiak,
I.(2020). The shift from early to late types of ribosomes in zebrafish development involves …

Ribonucleic acid (RNA) is an essential biomolecule in the domain of life. As a mediator
between the genetic information contained in deoxyribonucleic acid (DNA) and the cell, its …

Over one hundred types of chemical modifications have been characterized in cellular
RNAs. Pseudouridines (Ψ) and 2'-O-methylation of ribose sugars are the two most …