Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to
be a key factor in age-related macular degeneration (AMD) pathology. RPE cells are …

There is a mutualistic symbiotic relationship between the components of the
photoreceptor/retinal pigment epithelium (RPE)/Bruch's membrane (BrMb)/choriocapillaris …

Age-related macular degeneration (AMD) is a complex, degenerative and progressive eye
disease that usually does not lead to complete blindness, but can result in severe loss of …

Age-related macular degeneration (AMD) is a leading cause of irreversible blindness in the
world. Although the etiology and pathogenesis of AMD remain largely unclear, a complex …

Age-related macular degeneration (AMD) is a disease of the outer retina, characterized most
significantly by atrophy of photoreceptors and retinal pigment epithelium accompanied with …

Mitochondrial dysfunctions have been implicated in the pathophysiology of several age-
related diseases including age-related macular degeneration (AMD), a progressive …

Age-related macular degeneration (AMD) is a late-onset, neurodegenerative retinal disease
that shares several clinical and pathological features with Alzheimer's disease (AD) …

Genetic variants at chromosomes 1q31-32 and 10q26 are strongly associated with
susceptibility to age-related macular degeneration (AMD), a common blinding disease of the …

Mitochondria are central in retinal cell function and survival and they perform functions that
are critical to cell function. Retinal neurons have high energy requirements, since large …

It has previously been reported that antioxidant vitamins can help reduce the risk of vision
loss associated with progression to advanced age-related macular degeneration (AMD), a …