[HTML][HTML] Emergence of antibiotic resistance Pseudomonas aeruginosa in intensive care unit; a critical review

P Pachori, R Gothalwal, P Gandhi - Genes & diseases, 2019 - Elsevier
The emergence of antibiotic resistant bacteria in the healthcare is a serious concern. In the
Healthcare premises precisely intensive care unit are major sources of microbial diversity …

Fitness costs of plasmids: a limit to plasmid transmission

A San Millan, RC MacLean - Microbiology spectrum, 2017 - Am Soc Microbiol
Plasmids mediate the horizontal transmission of genetic information between bacteria,
facilitating their adaptation to multiple environmental conditions. An especially important …

Systematic review and meta-analysis of clinical and economic outcomes from the implementation of hospital-based antimicrobial stewardship programs

S Karanika, S Paudel, C Grigoras… - Antimicrobial agents …, 2016 - Am Soc Microbiol
The implementation of antimicrobial stewardship programs (ASPs) is a promising strategy to
help address the problem of antimicrobial resistance. We sought to determine the efficacy of …

Origin and proliferation of multiple-drug resistance in bacterial pathogens

HH Chang, T Cohen, YH Grad… - Microbiology and …, 2015 - Am Soc Microbiol
Many studies report the high prevalence of multiply drug-resistant (MDR) strains. Because
MDR infections are often significantly harder and more expensive to treat, they represent a …

Diagnosis of sepsis with cell-free DNA by next-generation sequencing technology in ICU patients

Y Long, Y Zhang, Y Gong, R Sun, L Su, X Lin… - Archives of Medical …, 2016 - Elsevier
Background and Aims Bacteremia is a common serious manifestation of disease in the
intensive care unit (ICU), which requires quick and accurate determinations of pathogens to …

Susceptibility patterns and ESBL rates of Escherichia coli from urinary tract infections in Canada and the United States, SMART 2010–2014

SH Lob, LE Nicolle, DJ Hoban, KM Kazmierczak… - … and infectious disease, 2016 - Elsevier
Increasing antimicrobial resistance in urinary tract infections (UTI) is a concern. To evaluate
resistance trends, 3498 Escherichia coli UTI isolates were collected from 2010 to 2014 in the …

High burden of antimicrobial resistance among gram negative bacteria causing healthcare associated infections in a critical care unit of Nepal

NP Parajuli, SP Acharya, SK Mishra, K Parajuli… - … Resistance & Infection …, 2017 - Springer
Background Healthcare associated infections (HCAI) and antimicrobial resistance are
principal threats to the patients of intensive care units and are the major determining factors …

Intensive care unit sinks are persistently colonized with multidrug resistant bacteria and mobilizable, resistance-conferring plasmids

L Diorio-Toth, MA Wallace, CW Farnsworth, B Wang… - Msystems, 2023 - Am Soc Microbiol
Contamination of hospital sinks with microbial pathogens presents a serious potential threat
to patients, but our understanding of sink colonization dynamics is largely based on infection …

High burden of ESBL and carbapenemase-producing gram-negative bacteria in bloodstream infection patients at a tertiary care hospital in Addis Ababa, Ethiopia

D Beshah, AF Desta, GB Woldemichael… - PLoS …, 2023 - journals.plos.org
Background Bloodstream infection due to beta-lactamase and carbapenemase-producing
gram-negative bacteria poses a substantial challenge to the effectiveness of antimicrobial …

Effect of gram stain–guided initial antibiotic therapy on clinical response in patients with ventilator-associated pneumonia: the GRACE-VAP randomized clinical trial

J Yoshimura, K Yamakawa, Y Ohta… - JAMA network …, 2022 - jamanetwork.com
Importance Gram staining should provide immediate information for detecting causative
pathogens. However, the effect of Gram staining on restricting the initial antibiotic choice has …