Antibacterial electrospun nanofibrous materials for wound healing

Z Wang, W Hu, W Wang, Y Xiao, Y Chen… - Advanced Fiber …, 2023 - Springer
One of the leading causes of wound healing delays is bacterial infection, which limits the
process of restoring the histological and functional integrity of the skin. Electrospun …

Local and systemic mechanisms that control the hair follicle stem cell niche

B Zhang, T Chen - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Hair follicles are essential appendages of the mammalian skin, as hair performs vital
functions of protection, thermoregulation and sensation. Hair follicles harbour exceptional …

Emerging bioprinting for wound healing

Z Wang, X Liang, G Wang, X Wang… - Advanced …, 2023 - Wiley Online Library
Bioprinting has attracted much attention due to its suitability for fabricating biomedical
devices. In particular, bioprinting has become one of the growing centers in the field of …

[HTML][HTML] A stem cell aging framework, from mechanisms to interventions

B Liu, J Qu, W Zhang, JCI Belmonte, GH Liu - Cell reports, 2022 - cell.com
Stem cells play central roles in tissue development, homeostasis, and regeneration.
Decades of scientific research have uncovered processes of stem cell decline in tissue and …

Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity

K Schönberger, N Obier, MC Romero-Mulero… - Cell stem cell, 2022 - cell.com
Hematopoietic stem cells (HSCs) rely on complex regulatory networks to preserve stemness.
Due to the scarcity of HSCs, technical challenges have limited our insights into the interplay …

Deciphering the molecular mechanisms of stem cell dynamics in hair follicle regeneration

JH Lee, S Choi - Experimental & Molecular Medicine, 2024 - nature.com
Hair follicles, which are connected to sebaceous glands in the skin, undergo cyclic periods
of regeneration, degeneration, and rest throughout adult life in mammals. The crucial …

Neural stem cell metabolism revisited: a critical role for mitochondria

V Scandella, F Petrelli, DL Moore, SMG Braun… - Trends in Endocrinology …, 2023 - cell.com
Metabolism has emerged as a key regulator of stem cell behavior. Mitochondria are crucial
metabolic organelles that are important for differentiated cells, yet considered less so for …

Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism

G Wang, E Sweren, W Andrews, Y Li, J Chen, Y Xue… - Science …, 2023 - science.org
Tissue injury induces metabolic changes in stem cells, which likely modulate regeneration.
Using a model of organ regeneration called wound-induced hair follicle neogenesis (WIHN) …

Psychological stress-induced microbial metabolite indole-3-acetate disrupts intestinal cell lineage commitment

W Wei, Y Liu, Y Hou, S Cao, Z Chen, Y Zhang, X Cai… - Cell Metabolism, 2024 - cell.com
The brain and gut are intricately connected and respond to various stimuli. Stress-induced
brain-gut communication is implicated in the pathogenesis and relapse of gut disorders. The …

Copper depletion strongly enhances ferroptosis via mitochondrial perturbation and reduction in antioxidative mechanisms

F Li, X Wu, H Liu, M Liu, Z Yue, Z Wu, L Liu, F Li - Antioxidants, 2022 - mdpi.com
Copper serves as a co-factor for a host of metalloenzymes, particularly cytochrome c
oxidase (COX). Although it is known that impaired COX function can lead to the excessive …